Fig. 6From: Effect of C-reactive protein deficiency on insulin resistance reversal in rats with polycystic ovary syndrome through augmented leptin actionCRP deficiency enhance the role of central leptin on restoring insulin sensitivity during lipid infusion in PCOS rats fed a ND. (a) Experimental procedure and EHC protocol. (b) GIR time course (c) Cumulative GIR. (d) Hepatic glucose production (HGP). (e) Percentage of suppression of HGP. (f) Glucose disappearance rates (GRD). (g) RT-PCR assays of hepatic PEPCK mRNA (h, i) Immunoblotting assays of hepatic expression of PEPCK protein, phosphorylation of InsR and Akt and densitometric quantification. Data are expressed as the mean ± SEM (n = 5–6 rats for each group). *P < 0.05, **P < 0.01 vs. ND-DHEA-WT groupBack to article page