Fig. 1

Changes in body weight and food intake in 4-month-old female rats. Four-week-old of placebo or dehydroepiandrosterone (DHEA)-treated female WT and CRP KO rats were fed a ND or HFD for 3 month. (a, d) Body weight gain curve. (b, e) Cumulative body weight. (c ,f) Average daily food intake. Data are expressed as the mean ± SEM (n = 6 rats for each group). ND, normal chow diet; HFD, high-fat diet. ^*P < 0.05 vs. ND-WT group; ^#P < 0.05 vs. ND-DHEA-WT group; ^**P < 0.05 vs. HFD-WT group, ^##P < 0.05 vs. HFD-DHEA-WT group