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Table 5 Multivariate Cox regression analyses for MACE

From: The metabolic score for insulin resistance in the prediction of major adverse cardiovascular events in patients after coronary artery bypass surgery: a multicenter retrospective cohort study

MTES-IR

Incident MACE,

n (%)

HR (95% CI)

Model1

Model2

Model3

Per 1 Unit increase

243 (22.1%)

1.05 (1.03–1.07) **

1.04 (1.03–1.06) **

1.05 (1.03–1.07) **

Per 1 SD increase

 

1.40 (1.24–1.60) **

1.35 (1.19–1.53) **

1.36 (1.20–1.55) **

Quartile 1

48 (17.4%)

1 (Reference)

1 (Reference)

1 (Reference)

Quartile 2

51 (18.4%)

1.12 (0.75–1.66)

1.09 (0.73–1.62)

1.08 (0.72–1.60)

Quartile 3

62 (22.5%)

1.47 (1.00–2.14) *

1.34 (0.91–1.97)

1.34 (0.91–1.98)

Quartile 4

82 (30.3%)

2.19 (1.53–3.14) **

1.94 (1.34–2.79) **

1.97 (1.36–2.86) **

p for trend

 

 < 0.001

 < 0.001

 < 0.001

  1. Model 1: adjusted for age and gender
  2. Model 2: adjusted for variables with p-value < 0.10, including age, hypertension, DM, previous stroke, LVEF, eGFR,   TC, LDL-C, beta-blockers
  3. Model 3: adjusted for age, gender, previous MI, previous stroke, previous PCI, admission for MI, hypertension, DM, hyperlipidemia, FH-CAD, TC, LDL-C, eGFR, LVEF, antiplatelet drugs, beta-blockers, statins, ACEI/ARB and hypoglycemic drugs
  4. MACE the major adverse cardiovascular events, METS-IR the metabolic score for insulin resistance, HR hazard ratio, CI confidence interval, SD standard deviation
  5. p values in bold are < 0.05
  6. *p < 0.05
  7. **p < 0.001
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Diabetology & Metabolic Syndrome

ISSN: 1758-5996

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