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Table 3 Association of TyG index with all-cause and cardiovascular mortality in the total population and stratified by sex

From: Sex differences in the nonlinear association of triglyceride glucose index with all-cause and cardiovascular mortality in the general population

TyG index

Age-standardized mortality rate, %

HR (95% CI), P-value

Model 1

 

Model 2

 

Model 3

 

All-cause mortality

      

All participants

      

Tertiles

       

T 1 (6.56–8.28)

10.00%

1.23 (0.97, 1.56)

0.081

1.24 (0.93, 1.65)

0.136

1.24 (0.93, 1.66)

0.142

T 2 (8.28–8.83)

7.92%

1 [Reference]

1 [Reference]

1 [Reference]

T 3 (8.83–13.3)

13.01%

1.33 (1.10, 1.62)

0.004

1.47 (1.16, 1.87)

0.001

1.38 (1.08, 1.77)

0.01

Males

       

Tertiles

       

T 1 (6.96–8.35)

11.92%

1.51 (1.12, 2.03)

0.006

1.48 (1.02, 2.16)

0.038

1.52 (1.03, 2.24)

0.034

T 2 (8.35–8.91)

11.06%

1 [Reference]

1 [Reference]

1 [Reference]

T 3 (8.91–13.3)

15.47%

1.64 (1.26, 2.13)

< 0.001

2.05 (1.47, 2.85)

< 0.001

2.14 (1.51, 3.01)

< 0.001

Females

       

Tertiles

       

T 1 (6.56–8.22)

8.10%

1.32 (0.90, 1.94)

0.151

1.46 (0.94, 2.27)

0.093

1.56 (1.06, 2.44)

0.041

T 2 (8.22–8.77)

5.64%

1 [Reference]

1 [Reference]

1 [Reference]

T 3 (8.77–13.05)

10.42%

1.21 (0.89, 1.64)

0.229

1.15 (0.81, 1.65)

0.431

1.07 (0.73, 1.54)

0.738

Cardiovascular mortality

      

All participants

      

Tertiles

       

T 1 (6.56–8.55)

2.69%

1.35 (0.92, 1.97)

0.126

1.37 (0.85, 2.22)

0.2

1.46 (0.89, 2.39)

0.135

T 2 (8.55–9.35)

2.63%

1 [Reference]

1 [Reference]

1 [Reference]

T 3 (9.35–13.3)

3.89%

1.44 (0.93, 2.23)

0.105

1.47 (0.85, 2.55)

0.168

1.35 (0.74, 2.47)

0.327

Males

       

Tertiles

       

T 1 (6.95–8.55)

3.88%

1.31 (0.82, 2.12)

0.262

1.35 (0.72, 2.55)

0.351

1.56 (0.81, 3.02)

0.185

T 2 (8.55–9.35)

3.32%

1 [Reference]

1 [Reference]

1 [Reference]

T 3 (9.35–13.3)

4.10%

1.35 (0.78, 2.36)

0.282

1.57 (0.78, 3.15)

0.206

1.78 (0.83, 3.83)

0.14

Females

       

Tertiles

       

T 1 (6.56–8.55)

1.96%

1.35 (0.72, 2.54)

0.353

1.24 (0.53, 2.48)

0.739

1.17 (0.48, 2.40)

0.866

T 2 (8.55–9.35)

1.75%

1 [Reference]

1 [Reference]

1 [Reference]

T 3 (9.35–13.3)

3.62%

1.56 (0.76, 3.21)

0.23

1.16 (0.46, 2.92)

0.751

0.78 (0.26, 2.28)

0.644

  1. Model 1: Adjusted for survey cycle, age
  2. Model 2: Adjusted for survey cycle, age, sex (only for all participants), education, smoking, BMI, LDL-C, HDL-C, and eGFR.
  3. Model 3: Adjusted for survey cycle, age, sex (only for all participants), education, smoking, BMI, LDL-C, HDL-C, eGFR, diabetes, hypertension, CAD, cancer, statins, and glucose-lowering drugs
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Diabetology & Metabolic Syndrome

ISSN: 1758-5996

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