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Fig. 2 | Diabetology & Metabolic Syndrome

Fig. 2

From: Therapeutic effects on the development of heart failure with preserved ejection fraction by the sodium-glucose cotransporter 2 inhibitor dapagliflozin in type 2 diabetes

Fig. 2

Dapagliflozin improved left ventricular diastolic function and myocardial hypertrophy in ZDF rats. a–d Key parameters obtained from invasive left cardiac catheterization. e Representative LV pressure–volume (P–V) loops and the slope of EDPVR. f Representative images of M-mode echocardiography. g HE staining of heart sections is presented. Bar = 100 μm, Magnification = ×40. h The cardiomyocyte diameter/TL ratio was calculated. i Correlation analysis between cardiomyocyte diameter/TL and the slope of EDPVR. Data are the mean ± SD. n = 8 per group. *P < 0.05 vs. Lean; #P < 0.05 vs. ZDF

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Diabetology & Metabolic Syndrome

ISSN: 1758-5996

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