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Table 2 Baseline clinical characteristics of the population used in the experimental verification groups

From: 12,13-diHOME and noradrenaline are associated with the occurrence of acute myocardial infarction in patients with type 2 diabetes mellitus

 

T2DM (n = 126)

T2DM + AMI (n = 122)

P value

Age, years

63 (57–76)

62 (55–70)

0.684

Male gender, n (%)

54 (42.9)

89 (73)

 < 0.001

BMI, Kg/m2

26.46 (23.64–28.58)

25.95 (24.17–27.71)

0.283

Smoking, n (%)

24 (19)

75 (61.5)

 < 0.001

Hypertension, n (%)

40 (31.7)

76 (62.3)

 < 0.001

Dyslipidemia, n (%)

78 (61.9)

65 (53.3)

0.169

Duration of diabetes, years

9.0 (3.0–15.0)

10.0 (3.3–15.0)

0.811

Laboratory values

 Cr, umol/L

62.05 (53.03–71.28)

73.40 (60.08–82.63)

0.001

 TC, mmol/L

3.99 (3.31–4.60)

4.46 (3.85–5.04)

 < 0.001

 TG, mmol/L

1.38 (1.06–1.97)

1.36 (1.02–2.08)

0.697

 HDL-C, mmol/L

1.06 (0.92–1.27)

0.96 (0.86–1.14)

0.014

 LDL-C, mmol/L

2.20 (1.69–2.65)

2.65 (2.28–3.10)

 < 0.001

 Hs-CRP, mg/L

1.00 (0.46–2.97)

13.25 (2.57–29.29)

 < 0.001

 HbA1c, %

6.80 (6.20–7.50)

7.90 (6.95–9.13)

 < 0.001

 Fasting glucose, mmol/L

6.60 (5.46–7.54)

9.24 (6.71–12.34)

 < 0.001

 CK-MB, ng/ml

1.00 (0.70–1.55)

5.15 (1.93–20.35)

 < 0.001

 cTNI, ng/ml

0 (0–0)

0.67 (0.66–6.93)

 < 0.001

Medical therapies before admission

 Antiplatelet agent, n (%)

32 (25.4)

24 (19.7)

0.281

 Statin, n (%)

45 (35.7)

12 (9.8)

 < 0.001

 ACEI/ARB, n (%)

63 (50)

35 (28.7)

 < 0.001

 Diuretics, n (%)

14 (11.1)

7 (5.7)

0.129

 Acarbose, n (%)

42 (33.3)

54 (44.3)

0.077

 Metformin, n (%)

76 (60.3)

44 (36.1)

 < 0.001

 Sulfonylurea, n (%)

33 (26.2)

29 (23.8)

0.660

 Insulin, n (%)

29 (23)

30 (24.6)

0.771

 Insulin sensitizers, n (%)

10 (7.9)

4 (3.3)

0.112

 DPP-4 inhibitors, n (%)

5 (4)

2 (1.6)

0.268

  1. Data are expressed as mean ± standard deviation, numbers (%) or median (interquartile range)
  2. T2DM diabetes mellitus, AMI acute myocardial infarction, BMI body mass index, Cr creatinine, TC total cholesterol, TG triglyceride, HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol, Hs-CRP hypersensitive C-reactive protein, HbA1c hemoglobin A1c, CK-MB creatine kinase isoenzyme, cTNI cardiac troponin I, ACEI/ARB angiotensin-converting enzyme inhibitors/angiotensin receptor blocker, DPP-4 dipeptidyl peptidase-IV