Table 1 Baseline clinical characteristics of the population used for the untargeted metabolomic analysis
Control (n = 28) | T2DM (n = 30) | T2DM + AMI (n = 24) | P value | |
|---|---|---|---|---|
Age, years | 58.89 ± 9.7 | 59.47 ± 9.4 | 62.71 ± 11.3 | 0.353 |
Male gender, n (%) | 14 (50.0) | 15 (50.0) | 12 (50.0) | 1.00 |
BMI, Kg/m2 | 24.80 ± 3.54 | 26.03 ± 3.17 | 25.29 ± 3.26 | 0.370 |
Smoking, n (%) | 13 (46.4) | 11 (36.7) | 12 (50) | 0.585 |
Duration of diabetes, years | – | 1.0 (1.0–4.0) | 1.0 (1.0–2.3) | 0.243 |
Laboratory values | ||||
Cr, umol/L | 64.10 (52.20–76.10) | 62.30 (52.30–69.80) | 67.90 (52.78–78.63) | 0.358 |
TC, mmol/L | 4.16 (3.70–5.02) | 4.13 (3.54–4.75) | 4.19 (3.50–4.56) | 0.306 |
TG, mmol/L | 1.00 (0.77–1.74) | 1.33 (1.03–1.98) | 1.52 (0.90–2.36) | 0.118 |
HDL-C, mmol/L | 1.25 (1.13–1.61) | 0.98 (0.87–1.26)_ | 1.01 (0.85–1.29) | 0.002 |
LDL-C, mmol/L | 2.30 (1.87–2.72) | 2.28 (1.94–2.75) | 2.39 (1.80–2.82) | 0.738 |
Hs-CRP, mg/L | 0.63 (0.38–2.48) | 1.08 (0.54–3.58) | 8.67 (3.16–27.15) | < 0.001 |
HbA1c, % | 5.50 (5.30–5.70) | 6.50 (6.20–7.30) | 7.50 (6.73–9.08) | < 0.001 |
Fasting glucose, mmol/L | 4.85 ± 0.41 | 6.46 ± 1.34 | 10.07 ± 3.80 | < 0.001 |
CK-MB, ng/ml | 1.00 (0.60–1.30) | 0.80 (0.50–1.10) | 6.35 (2.15–23.45) | < 0.001 |
cTNI, ng/ml | 0 (0–0) | 0 (0–0) | 0.41 (0.06–10.74) | < 0.001 |