Table 1 Baseline clinical and laboratory characteristics of the groups
SGLT2i (n = 22) | Control (n = 20) | p-value | |
|---|---|---|---|
Age (years) | 65 ± 10 | 64 ± 6 | 0.82 |
Male sex | 14 (63%) | 15 (75%) | 0.42 |
Arterial hypertension | 19 (86%) | 14 (70%) | 0.83 |
Active smoker | 12 (54%) | 9 (45%) | 0.41 |
Previous stroke | 5 (22%) | 2 (10%) | 0.26 |
Peripheral arterial disease | 2 (9%) | 1 (5%) | 0.60 |
eGFR (mL/min/1.73m2) | 62.10 ± 22.50 | 68.20 ± 17.70 | 0.10 |
Mehran score | 6.70 ± 3.68 | 5.55 ± 2.09 | 0.44 |
LVEF (%) | 50 ± 14% | 60.00 ± 9.16 | 0.18 |
Prior PCI (%) | 5 (22%) | 3 (15%) | 0.52 |
Prior CABG (%) | 4 (18%) | 2 (10%) | 0.44 |
Hemoglobin (g/dL) | 11.8 ± 4.6 | 12.5 ± 4.0 | 0.50 |
Platelets (mm3) | 220,000 ± 71,554 | 209,750 ± 41,079 | 0.23 |
Troponin (ng/mL) | 56 ± 101 | 24 ± 43 | 0.18 |
CKMB (ng/mL) | 2.32 ± 1.37 | 1.32 ± 0.75 | 0.016 |
Glycated hemoglobin (%) | 6.3 ± 3.0 | 7.6 ± 2.0 | 0.16 |
Urea (mg/mL) | 47.68 ± 17.00 | 45.10 ± 31.20 | 0.64 |
Creatinine (mg/mL) | 1.24 ± 0.35 | 1.06 ± 0.26 | 0.24 |
Total cholesterol (mg/mL) | 178 ± 55 | 160 ± 46 | 0.16 |
HDL-cholesterol (mg/mL) | 47 ± 13 | 40 ± 9 | 0.037 |
LDL-cholesterol (mg/mL) | 98 ± 41 | 96 ± 40 | 0.92 |
Triglycerides (mg/mL) | 148 ± 63 | 144 ± 55 | 0.87 |