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Table 4 Mediation analysis of hs-CRP on the association of pregnancy loss history with GDM

From: The mediating role of inflammation in the association between pregnancy loss history and gestational diabetes mellitus

Effects

Pregnancy loss

Induced abortion

Miscarriage

Total effect

0.31(0.07, 0.56)

0.27(0.12, 0.42)

0.07(-0.15, 0.28)

Direct effect

0.23(0.03, 0.44)

0.22(0.09, 0.34)

0.07(-0.12, 0.25)

Indirect effect

0.08(0.04, 0.12)

0.05(0.03, 0.08)

0.00(-0.03, 0.04)

Proportion mediated (%)

25.6

20.4

^

  1. The model was adjusted for maternal age, pre-pregnancy BMI, educational level, parity, and family history of diabetes
  2. ^ Mediating effects not significant