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Table 3 Association between hs-CRP concentration and risk of GDM

From: The mediating role of inflammation in the association between pregnancy loss history and gestational diabetes mellitus

hs-CRP (mg/L)

n(%)

RR(95% CI)

  

Crude model

 

Adjusted model

Log-transformed hs-CRP

841(17.3)

1.13(1.11, 1.15)

 

1.12(1.10, 1.14)

T1(< 2.0)

169(10.4)

1.00 (ref.)

 

1.00 (ref.)

T2(2.0-4.3)

248(15.2)

1.54(1.25, 1.90)

 

1.41(1.14, 1.74)

T3(≥ 4.3)

424(26.3)

3.07(3.53, 3.72)

 

2.57(2.09, 3.15)

P trend

 

< 0.001

 

< 0.001

Q1(< 1.5)

136(11.0)

1.00 (ref.)

 

1.00 (ref.)

Q2(1.5-3.0)

148(12.3)

1.13(0.88, 1.45)

 

1.07(0.83, 1.37)

Q3(3.0-5.1)

209(17.2)

1.67(1.33, 2.11)

 

1.47(1.16, 1.86)

Q4(≥ 5.1)

348(28.6)

3.23(2.60, 4.01)

 

2.63(2.09, 3.30)

P trend

 

< 0.001

 

< 0.001

  1. T, tertile; Q, quartile
  2. Adjusted model: Adjusted for maternal age, pre-pregnancy BMI, educational level, parity, and family history of diabetes
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Diabetology & Metabolic Syndrome

ISSN: 1758-5996

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