Table 4 Effect of the interaction between time factor and albuminuria on the studied parameters
Parameter | Normo-albuminuria | Microalbuminuria | Time*Group interaction | ||||||
|---|---|---|---|---|---|---|---|---|---|
Before | During | After | Before | During | After | F value | P value | Partial η2 | |
BMI (kg/m2) | 28.1 ± 2.7 | 28.37± 2.75 | 28.96± 2.80 | 29.89± 3.60 | 30.47± 3.67 | 30.89± 3.50 | 1.601 | 0.209 | 0.019 |
SBP (mmHg) | 135.2 ± 9.3 | 132.29± 9.08 | 132.50± 9.20 | 134.75± 7.95 | 131.69± 8.98 | 134.66± 9.37 | 1.052 | 0.352 | 0.013 |
DBP (mmHg) | 83.5 ± 4.8 | 82.50± 5.71 | 85.21± 6.33 | 85.08± 6.12 | 80.93± 5.45 | 84.58± 8.110 | 1.344 | 0.264 | 0.016 |
MAP (mmHg) | 100.8 ± 5.8 | 99.10± 6.35 | 100.97± 6.36 | 101.64± 6.24 | 97.85± 6.0 | 101.27± 8.08 | 0.737 | 0.480 | 0.009 |
Haemoglobin (g/dL) | 13.3 ± 1.9 | 13.0± 1.82 | 13.15± 1.35 | 13.47± 1.69 | 13.24± 1.74 | 13.20± 1.09 | 0.134 | 0.875 | 0.002 |
HBA1c % | 6.96 ± 0.36 | 7.35± 0.49 | 8.34± 0.35 | 7.0± 0.43 | 7.42± 0.50 | 8.45± 0.51 | 0.042 | 0.946 | 0.001 |
BUN (mg/dL) | 13.96 ± 3.5 | 25.21± 2.85 | 21.04± 3.99 | 16.19± 4.16 | 27.64± 3.95 | 23.51± 4.618 | 0.035 | 0.941 | 0.000 |
Serum creatinine(mg/dL) | 1.05 ± 0.11 | 1.13± 0.15 | 0.98± 0.13 | 1.10± 0.11 | 1.25± 0.17 | 1.10± 0.19 | 2.906 | 0.065 | 0.035 |
eGFR (ml/ min/1.73 m²) | 72.33± 12.31 | 67.04± 14.09 | 79.0± 14.13 | 70.80± 15.80 | 61.75± 15.69 | 72.27± 21.21 | 1.338 | 0.260 | 0.016 |
Serum uric acid(mg/dL) | 6.84± 0.812 | 7.82± 1.17 | 6.40± 1.05 | 6.76± 0.90 | 7.72± 1.472 | 6.14± 0.98 | 0.308 | 0.736 | 0.004 |
Total cholesterol(mg/dL) | 223.3 ± 36.9 | 212.9 ± 41.2 | 212.7 ± 32.6 | 212.7 ± 33.7 | 203.7 ± 35.8 | 208.9 ± 31.1 | 0.389 | 0.545 | 0.005 |
Triglycerides(mg/dL) | 260.5± 57.77 | 270.0± 59.55 | 216.75± 66.7 | 269.24± 63.5 | 281.46± 86.8 | 214.61± 55.4 | 0.252 | 0.653 | 0.003 |
HDL-C (mg/dL) | 42.67± 6.91 | 38.0± 6.21 | 42.92± 12.09 | 42.29± 7.23 | 39.98± 7.23 | 43.22± 7.81 | 0.442 | 0.530 | 0.005 |
LDL-C(mg/dL) | 127.17± 31.9 | 119.25± 35.3 | 125.50± 27 | 116.14± 31.2 | 106.61± 33.7 | 124.81± 30.5 | 1.345 | 0.252 | 0.016 |
VLDL (mg/dL) | 49.92± 15.83 | 55.17± 14.84 | 43.17± 12.20 | 51.63± 15.33 | 56.27± 18.21 | 42.44± 10.91 | 0.188 | 0.698 | 0.002 |
TG / HDL | 6.20± 1.50 | 7.23± 1.755 | 5.52± 2.38 | 6.67± 2.44 | 7.32± 2.82 | 5.19± 1.80 | 0.667 | 0.433 | 0.008 |
NLR | 2.35± 0.67 | 11.83± 7.46 | 1.99± 0.93 | 2.10± 0.68 | 9.60± 7.97 | 1.78± 0.80 | 1.111 | 0.296 | 0.014 |
dNLR | 1.71± 0.38 | 5.93± 3.23 | 1.45± 0.62 | 1.6± 0.43 | 5.18± 3.61 | 1.32± 0.55 | 0.554 | 0.462 | 0.007 |
WBCs (× 109/L) | 6.56± 1.42 | 7.55± 2.57 | 6.19± 1.63 | 6.27± 1.72 | 7.57± 3.62 | 6.62± 1.95 | 0.703 | 0.467 | 0.009 |
ANC(×103/mcL) | 4.10± 1.03 | 6.31± 2.50 | 3.49± 1.0 | 3.80± 1.16 | 6.07± 3.55 | 3.65± 1.33 | 0.328 | 0.618 | 0.004 |
Albumin(g/dL) | 4.25± 0.208 | 4.37± 0.347 | 4.41± 0.481 | 4.20± 0.27 | 4.24± 0.39 | 4.20± 0.53 | 1.428 | 0.243 | 0.017 |
ALP(IU/L) | 67.79± 19.77 | 111.71± 28.3 | 96.71± 25.28 | 61.07± 21.53 | 91.81± 26.74 | 81.56± 27.19 | 3.131 | 0.062 | 0.037 |
Vitamin D3 (ng/mL) | 19.29± 4.99 | 24.0± 5.34 | 36.58± 9.141 | 21.69± 4.89 | 24.64± 8.23 | 37.64± 7.014 | 0.562 | 0.553 | 0.007 |
Intact PTH (pg/mL) | 39.39± 20.96 | 42.19± 19.23 | 40.17± 18.86 | 60.99± 23.92 | 67.33± 26.18 | 63.11± 25.05 | 1.165 | 0.309 | 0.014 |
Calcium(mg/dL) | 10.16± 0.53 | 9.07± 0.41241 | 9.33± 0.49 | 9.76± 0.80 | 9.02± 0.53 | 9.18± 0.66 | 2.198 | 0.121 | 0.026 |
Magnesium(mg/dL) | 2.01± 0.14 | 2.00± 0.19 | 2.12± 0.20 | 2.03± 0.183 | 2.03± 0.18 | 2.16± 0.19 | 0.164 | 0.826 | 0.002 |
Phosphorus(mg/dL) | 3.69± 0.62 | 4.55± 0.39 | 4.10± 0.36 | 3.75± 0.54 | 4.49± 0.56 | 4.04± 0.60 | 0.687 | 0.481 | 0.008 |