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Table 2 75 g-OGTT parameters and HDP in individuals with RBG of ≥ 100 mg/dL (n = 802)

From: Evaluating glucose variability through OGTT in early pregnancy and its association with hypertensive disorders of pregnancy in non-diabetic pregnancies: a large-scale multi-center retrospective study

 

HDP (n = 115)

EoHDP (n = 25)

LoHDP (n = 90)

cOR

(95%CI)

aOR§

(95%CI)

cOR

(95%CI)

aOR§

(95%CI)

cOR

(95%CI)

aOR§

(95%CI)

Age, years

1.02

(0.98–1.06)

1.00

(0.96–1.05)

0.98

(0.90–1.05)

0.96

(0.88–1.05)

1.02

(0.98–1.07)

1.02

(0.97–1.07)

Pre-pregnant BMI, kg/m2

1.16*

(1.11–1.21)

1.16*

(1.11–1.21)

1.15*

(1.08–1.23)

1.17*

(1.08–1.26)

1.13*

(1.09–1.18)

1.13*

(1.08–1.19)

Primiparity

1.51*

(1.02–2.24)

1.58*

(1.02–2.46)

0.99

(0.44–2.21)

0.99

(0.42–2.32)

1.67*

(1.07–2.59)

1.72*

(1.06–2.78)

ART

1.77*

(1.06–2.94)

1.99*

(1.10–3.58)

1.23

(0.41–3.66)

1.95

(0.57–6.72)

1.87*

(1.08–3.25)

1.88

(1.00–3.54)

FPG†

1.48*

(1.01–2.18)

1.13

(0.73–1.75)

2.10*

(1.00–4.40)

1.82

(0.81–4.08)

1.29

(0.84–1.98)

0.92

(0.56–1.51)

Initial-increase†

1.29*

(1.14–1.47)

1.20*

(1.02–1.42)

1.22

(1.00–1.57)

1.57*

(1.15–2.15)

1.29*

(1.12–1.48)

1.08

(0.90–1.30)

Subsequent-decrease†

1.36*

(1.17–1.58)

1.12

(0.92–1.37)

0.88

(0.65–1.18)

0.56*

(0.38–0.82)

1.52*

(1.28–1.81)

1.38*

(1.11–1.73)

  1. Bold values represent statistically significant
  2. RBG random blood glucose levels, HDP hypertensive disorders of pregnancy, EoHDP early-onset HDP, LoHDP late-onset HDP, cOR crude odds ratio, aOR adjusted odds ratio, 95% CI 95% confidence interval, BMI body mass index, ART assisted reproductive technology, FPG fasting plasma glucose level
  3. §aORs were adjusted for maternal age, pre-pregnant BMI, primiparity, ART, FPG, initial-increase, and subsequent-decrease
  4. †per 20-mg/dL increment
  5. *Statistically significant