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Table 6 Subtypes analysis of pregnant women with twin pregnancies GDM according to OGTT results

From: Association between serum lipid profile during the first and second trimester of pregnancy as well as their dynamic changes and gestational diabetes mellitus in twin pregnancies: a retrospective cohort study

 

FPG

Non-FPG

Adjust OR

95% CI

P value

Adjust OR

95% CI

P value

First trimester

 CHO

  ≤ 3.84

1

  

1

  

  3.84–4.29

1.157

0.635–2.105

0.634

0.905

0.61–1.343

0.621

  4.29–4.80

1.204

0.662–2.188

0.543

1.03

0.62–1.711

0.908

  > 4.80

1.423

0.79–2.562

0.240

0.743

0.371–1.49

0.403

 TG

  ≤ 0.96

1

  

1

  

  0.96–1.27

1.009

0.532–1.913

0.978

1.68

1.2–2.351

0.003

  1.27–1.67

1.626

0.89–2.97

0.114

1.691

1.185–2.412

0.004

  > 1.67

2.076

1.13–3.815

0.019

2.526

1.739–3.67

< 0.01

 HDL

  ≤ 1.35

1

  

1

  

  1.35–1.60

0.839

0.489–1.438

0.522

0.771

0.552–1.076

0.126

  1.60–1.87

1.044

0.598–1.823

0.879

1.144

0.756–1.732

0.525

  > 1.87

0.934

0.53–1.648

0.815

0.989

0.571–1.714

0.970

 LDL

  ≤ 1.71

1

  

1

  

  1.71–2.06

0.940

0.527–1.676

0.834

1.319

0.854–2.036

0.211

  2.06–2.47

1.037

0.586–1.837

0.901

1.323

0.754–2.32

0.330

  > 2.47

1.192

0.685–2.073

0.535

1.481

0.742–2.956

0.265

 LDL/HDL

  ≤ 0.99

1

  

1

  

  0.99–1.30

1.194

0.684–2.084

0.533

0.892

0.58–1.373

0.604

  1.30–1.65

0.740

0.394–1.39

0.348

1.292

0.739–2.258

0.369

  > 1.65

1.322

0.746–2.343

0.338

1.133

0.551–2.328

0.735

Second trimester

 CHO

  ≤ 5.49

1

  

1

  

  5.49–6.21

0.780

0.382–1.594

0.496

1.523

0.885–2.621

0.129

  6.21–7.02

0.888

0.448–1.763

0.735

1.618

0.75–3.49

0.220

  > 7.02

0.629

0.29–1.363

0.240

2.595

0.923–7.298

0.071

 TG

  ≤ 2.12

1

  

1

  

  2.12–2.69

1.287

0.601–2.754

0.516

1.319

0.852–2.042

0.214

  2.69–3.33

1.236

0.577–2.649

0.586

1.707

1.098–2.654

0.018

  > 3.33

1.389

0.642–3.002

0.404

2.134

1.303–3.496

0.003

 HDL

  ≤ 1.55

1

  

1

  

  1.55–1.80

0.957

0.499–1.834

0.894

0.863

0.566–1.314

0.491

  1.80–2.10

0.402

0.179–0.903

0.027

0.748

0.447–1.251

0.268

  > 2.10

0.390

0.171–0.893

0.026

0.770

0.388–1.527

0.455

 LDL

  ≤ 2.52

1

  

1

  

  2.52–3.15

1.008

0.497–2.043

0.983

1.038

0.622–1.734

0.886

  3.15–3.87

0.927

0.44–1.956

0.843

1.235

0.603–2.532

0.564

  > 3.87

0.881

0.412–1.884

0.743

1.065

0.405–2.804

0.898

 LDL/HDL

  ≤ 1.36

1

  

1

  

  1.36–1.73

2.721

1.23–6.017

0.013

1.240

0.781–1.97

0.362

  1.73–2.18

2.269

1.015–5.072

0.046

1.264

0.676–2.365

0.464

  > 2.18

1.494

0.626–3.563

0.365

1.545

0.669–3.567

0.308

  1. Bold values represent P < 0.05
  2. Adjusted age, pre-pregnancy BMI, family history of diabetes, IVF-ET, PCOS and FPG in first and second trimester
  3. FPG fasting plasma glucose, CHO total cholesterol, HDL high density lipoprotein-cholesterol, LDL low density lipoprotein-cholesterol
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Diabetology & Metabolic Syndrome

ISSN: 1758-5996

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