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Table 4 Logistics regression analysis of the risk of twin pregnancies GDM based on lipid stratification in the first trimester

From: Association between serum lipid profile during the first and second trimester of pregnancy as well as their dynamic changes and gestational diabetes mellitus in twin pregnancies: a retrospective cohort study

 

Adjust OR

95%CI

P value

Adjust OR

95% CI

P value

Age < 35

Age ≥ 35

TG

 ≤ 0.96

1

  

1

  

 0.96–1.27

1.572

1.072–2.306

0.021

1.435

0.901–2.287

0.128

 1.27–1.67

1.452

0.975–2.162

0.066

1.929

1.208–3.081

0.006

 > 1.67

1.804

1.188–2.74

0.006

2.719

1.719–4.298

< 0.001

LDL/HDL

 ≤ 0.99

1

  

1

  

 0.99–1.30

1.117

0.765–1.632

0.566

0.814

0.526–1.262

0.358

 1.30–1.65

1.157

0.789–1.696

0.456

1.138

0.743–1.743

0.553

 > 1.65

1.399

0.951–2.057

0.088

0.908

0.585–1.41

0.668

 

Pre-pregnancy BMI < 24

Pre-pregnancy BMI ≥ 24

TG

 ≤ 0.96

1

  

1

  

 0.96–1.27

1.63

1.157–2.296

0.005

1.088

0.601–1.971

0.780

 1.27–1.67

1.679

1.169–2.411

0.005

1.348

0.768–2.368

0.299

 > 1.67

2.281

1.568–3.32

< 0.001

1.841

1.071–3.164

0.027

LDL/HDL

 ≤ 0.99

1

  

1

  

 0.99–1.30

0.977

0.705–1.356

0.891

0.822

0.453–1.493

0.52

 1.30–1.65

1.224

0.88–1.703

0.23

0.892

0.512–1.553

0.686

 > 1.65

1.156

0.811–1.649

0.423

0.975

0.578–1.643

0.923

 

Assist pregnancy

Natural conception

TG

 ≤ 0.96

1

  

1

  

 0.96–1.27

1.674

1.092–2.568

0.018

1.344

0.882–2.047

0.169

 1.27–1.67

1.728

1.131–2.64

0.011

1.583

1.009–2.481

0.045

 > 1.67

2.156

1.413–3.289

< 0.001

2.617

1.644–4.168

< 0.001

LDL/HDL

 ≤ 0.99

1

  

1

  

 0.99–1.30

0.889

0.61–1.294

0.539

1.067

0.686–1.662

0.772

 1.30–1.65

1.094

0.757–1.579

0.633

1.232

0.79–1.92

0.357

 > 1.65

1.035

0.718–1.493

0.853

1.4

0.874–2.243

0.162

  1. Bold values represent P < 0.05
  2. Adjusted age, pre-pregnancy BMI, family history of diabetes, IVF-ET, PCOS and FPG in first trimester
  3. FPG fasting plasma glucose, CHO total cholesterol, HDL high density lipoprotein-cholesterol, LDL low density lipoprotein-cholesterol
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Diabetology & Metabolic Syndrome

ISSN: 1758-5996

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