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Table 2 Multivariable-adjusted means of glucolipid metabolic markers by diabetes status and sex

From: Sexual dimorphism in mitochondrial dysfunction and diabetes mellitus: evidence from a population-based cohort study

 

Females

Males

 

No diabetes

Prediabetes

Undiagnosed diabetes

Diagnosed diabetes

No diabetes

Prediabetes

Undiagnosed diabetes

Diagnosed diabetes

CRP, mg/dL

0.5 ± 0.01

0.6 ± 0.03

0.7 ± 0.07

0.7 ± 0.04

0.3 ± 0.01

0.4 ± 0.02

0.6 ± 0.06

0.5 ± 0.04

HbA1c, %

5.2 ± 0.01

5.8 ± 0.02

7.3 ± 0.04

7.4 ± 0.02

5.3 ± 0.01

5.7 ± 0.01

7.4 ± 0.04

7.5 ± 0.02

HbA1c, mmol/mol

33.7 ± 0.10

39.7 ± 0.17

56.4 ± 0.45

57.6 ± 0.24

33.9 ± 0.1

39.1 ± 0.16

56.9 ± 0.39

58.4 ± 0.24

Insulin, pmol/L

65.6 ± 1.34

85.8 ± 2.11

111.8 ± 5.70

124.6 ± 3.29

71.4 ± 1.97

84.0 ± 2.67

108.3 ± 7.14

126.8 ± 4.56

 C-peptide (nmol/L)

0.8 ± 0.01

1.0 ± 0.02

1.1 ± 0.04

1.0 ± 0.02

0.8 ± 0.01

1.0 ± 0.02

1.1 ± 0.04

1.1 ± 0.03

HOMA-IR index

2.0 ± 0.05

3.1 ± 0.07

6.0 ± 0.20

5.5 ± 0.12

2.2 ± 0.10

2.9 ± 0.13

6.0 ± 0.35

6.3 ± 0.24

Glucose, mmol/L

4.9 ± 0.02

5.5 ± 0.03

8.2 ± 0.09

8.4 ± 0.05

5.0 ± 0.02

5.6 ± 0.03

8.4 ± 0.08

8.7 ± 0.05

HDL-C, mmol/L

1.5 ± 0.01

1.4 ± 0.01

1.3 ± 0.02

1.3 ± 0.01

1.3 ± 0.01

1.2 ± 0.01

1.2 ± 0.02

1.2 ± 0.01

LDL-C, mmol/L

3.0 ± 0.02

3.1 ± 0.03

3.0 ± 0.07

2.7 ± 0.04

3.0 ± 0.02

3.1 ± 0.02

3.0 ± 0.07

2.6 ± 0.04

TG, mmol/L

1.4 ± 0.01

1.6 ± 0.03

2.0 ± 0.07

2.1 ± 0.04

1.7 ± 0.02

1.8 ± 0.03

2.4 ± 0.08

2.2 ± 0.05

TC, mmol/L

5.1 ± 0.01

5.2 ± 0.02

5.1 ± 0.06

4.9 ± 0.03

5.0 ± 0.01

5.1 ± 0.02

5.1 ± 0.05

4.6 ± 0.03

  1. CRP, C-reactive protein; HbA1c, glycosylated hemoglobin; HOMA-IR, homeostasis model assessment for insulin resistance; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; TG, triglyceride; TC, Total cholesterol. All estimates were calculated after adjustment for age, race/ethnicity, BMI, smoking, physical activity, hypertension, and eGFR. P trend for each biomarker across diabetes status by sex was less than 0.001 estimated by multiple linear regression