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Table 2 Associations of serum bilirubin levels with lower limb atherosclerosis

From: High-normal serum bilirubin decreased the risk of lower limb atherosclerosis in type 2 diabetes: a real-world study

 

TB levels

 

CB levels

 

UCB levels

 

OR

95%CI

P value

 

OR

95%CI

P value

 

OR

95%CI

P value

 

Lower limb plaque

Model 1

0.802

0.750–0.857

< 0.001

 

0.923

0.868–0.982

0.011

 

0.798

0.749–0.850

< 0.001

 

Model 2

0.836

0.770–0.906

< 0.001

 

0.911

0.843–0.984

0.018

 

0.841

0.779–0.907

< 0.001

 

Model 3

0.837

0.772–0.908

< 0.001

 

0.913

0.844–0.986

0.021

 

0.841

0.779–0.908

< 0.001

 

Model 4

0.852

0.784–0.926

< 0.001

 

0.940

0.867–1.019

0.132

 

0.848

0.785–0.918

< 0.001

 

Model 5

0.875

0.797–0.960

0.005

 

0.947

0.865–1.036

0.234

 

0.871

0.798–0.951

0.002

 

Model 6

0.870

0.784–0.964

0.008

 

0.950

0.855–1.055

0.338

 

0.864

0.784–0.952

0.003

 

Lower limb stenosis

Model 1

0.728

0.673–0.787

< 0.001

 

0.746

0.692–0.804

< 0.001

 

0.793

0.736–0.855

< 0.001

 

Model 2

0.767

0.700-0.841

< 0.001

 

0.695

0.636–0.759

< 0.001

 

0.877

0.804–0.957

0.003

 

Model 3

0.789

0.719–0.867

< 0.001

 

0.706

0.645–0.772

< 0.001

 

0.901

0.824–0.984

0.021

 

Model 4

0.800

0.728–0.879

< 0.001

 

0.711

0.650–0.779

< 0.001

 

0.911

0.833–0.996

0.041

 

Model 5

0.819

0.736–0.912

< 0.001

 

0.736

0.666–0.814

< 0.001

 

0.930

0.840–1.029

0.160

 

Model 6

0.835

0.737–0.946

0.005

 

0.767

0.685–0.858

< 0.001

 

0.925

0.820–1.043

0.205

 
  1. Model 1: unadjusted
  2. Model 2: age, sex, and DD
  3. Model 3: Model 2 + smoking status, alcohol intake, hypertension, and obesity
  4. Model 4: Model 3 + use of APAs, AHAs, LLDs and IIAs
  5. Model 5: Model 4 + SBP, DBP, WC, WHR and BMI
  6. Model 6: Model 5 + ALT, AST, γ-GT, TTG, TC, HDL-C, LDL-C, Lp(a), eGFR, SUA, UAE, FPG, 2 h PPG, HbA1C, FCP, 2 h PCP, Fins, 2hins, and CRP