Table 1 Characteristics of patients diagnosed as T1D after at least 12 months as T2D and of patients directly diagnosed as T1D.
From: Reclassification of type 2 diabetes to type 1 diabetes in Asturias (Spain) between 2011 and 2020
Male | Female | Total | Total directly diagnosed as T1D | |
|---|---|---|---|---|
Patients (n) | 100 | 105 | 205 | 247 |
Age (years) | 56.2 ± 12.3 | 61.9 ± 12.9 | 59.1 ± 12.9 | 44.3 ± 12.0 |
Evolution time (years median, IQ25%-75%) | 9.6 (3.9–15.8) | 6.4 (2.5–13.4) | 7.8 (2.9–14.8) | - |
BMI (kg/m2) | 25.6 ± 3.8 | 25.7 ± 5.9 | 25.7 ± 5.0 | 24.6 ± 5.7 |
< 25 (%) | 49.3 | 56.6 | 53.2 | 60.5 |
25–30 (%) | 38.7 | 24.1 | 31.0 | 26.2 |
> 30 (%) | 12 | 19.3 | 15.8 | 13.3 |
HbA1c (%, mmol/mol) | 9.1 ± 2.1, 76 ± 23 | 9.2 ± 2.0, 77 ± 22 | 9.1 ± 2.1, 77 ± 22 | 11.0 ± 2.8 |
Insulin use (%) | 39.7 | 70.9 | 56.5 | - |
Autoimmune thyroid disease (%) | 17.2 | 29.1 | 23.3 | 14.4 |
Hypothyroidism (%) | 12.1 | 21.5 | 16.8 | 11.5 |
Hyperthyroidism (%) | 3.0 | 6.8 | 4.9 | 2.9 |
Family history of T1D (%) | 14.5 | 11.0 | 12.8 | 12.4 |
Pancreatic autoimmunity (%) | 96.9 | 94.2 | 95.5 | 94.0 |
GAD (%) | 81.6 | 83.5 | 82.6 | 84.4 |
IA2 (%) | 23.2 | 36.9 | 30.3 | 42.1 |
ZNT8 (%) | 26.5 | 30.5 | 28.7 | 50.0 |
C-peptide (ng/ml; median, IQ25%-75%) | 0.88 (0.27–1.39) | 0.88 (0.28–1.56) | 0.88 (0.28–1.45) | 1.15 (0.01-11.0) |