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Fig. 4 | Diabetology & Metabolic Syndrome

Fig. 4

From: Empagliflozin ameliorates diabetic cardiomyopathy via regulated branched-chain amino acid metabolism and mTOR/p-ULK1 signaling pathway-mediated autophagy

Fig. 4

Effect of empagliflozin on myocardial fibrosis in diabetic mice. A–C showed Masson staining of the mouse heart cross-section, corresponding to the fibrosis of the global heart, the interstitial myocardium, and the epicardium, respectively. D showed the percentage of collagen in A. E, F showed mRNA of collagen I and collagen III in cardiac tissue. Data were expressed as the mean ± SEM. **P < 0.01 versus CTRL; ##P < 0.01 versus DM

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