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Table 2 Biochemical parameters before and after two doses of the variant COVID-19 vaccines

From: A study of glycemic perturbations following two doses of COVID-19 vaccination for patients with diabetes: the impacts of vaccine type and anti-diabetes drugs

 

ChAd/ ChAd

Moderna/ Moderna

BNT/BNT

 

Before

After

P

Before

After

P

Before

After

P

AC sugar (mg/dL)

127.81

(32.04)

131.29

(39.76)

0.150

132.34

(40.31)

131.02

(31.15)

0.600

130.00

(38.48)

133.78

(34.77)

0.323

HbA1c (%)

7.13

(1.24)

7.18

(1.30)

0.279

7.19

(1.28)

7.27

(1.15)

0.196

7.09

(0.95)

7.34

(1.08)

0.012*

eGFR (ml/min/1.73m2) a

83.96

(31.11)

84.44

(32.78)

0.712

76.79

(29.94)

79.97

(32.52)

0.001*

89.23

(27.53)

93.24

(32.55)

0.030*

ALT (U/L)

27.73

(19.11)

29.39

(25.78)

0.227

28.92

(20.69)

29.00

(20.03)

0.943

34.21

(28.76)

38.45

(33.62)

0.271

Cholesterol (mg/dL)

159.61

(30.50)

163.14

(29.95)

0.137

160.46

(28.00)

164.98

(30.81)

0.006*

170.39

(36.76)

177.16

(35.99)

0.108

Triglyceride (mg/dL)

143.63

(83.23)

141.70

(74.29)

0.699

158.48

(167.68)

138.15

(79.05)

0.011*

202.55

(281.03)

179.60

(133.49)

0.318

HDL (mg/dL)

47.02

(11.35)

48.00

(13.37)

0.076

47.76

(13.81)

49.03

(14.83)

0.004*

44.46

(9.55)

46.15

(9.90)

0.009*

LDL (mg/dL)

90.12

(26.85)

92.69

(24.36)

0.169

89.18

(23.29)

93.09

(27.87)

0.005*

98.87

(28.67)

104.49

(32.34)

0.055

  1. * Significance: P value < 0.05
  2. a Exclude subjects with end-stage renal disease
  3. Note: AC = pre-meal, HbA1c = glycated hemoglobin, ALT = Alanine aminotransferase, eGFR = estimated glomerular filtration rate, HDL = high density lipoprotein, LDL = low density lipoprotein