Variable | No. of subjects | No. of T2DM cases | Crude HR (95% CI) | Adjusted HR (95% CI) |
|---|
Othe PPIs | 3336 | 845 | 1.00 | 1.00 |
Lansoprazole | 1668 | 235 | 0.69 (0.59–0.80) | 0.65 (0.56–0.76) |
- Hazard ratios were adjusted for age, sex, index date, comorbidities, including heart failure, malignant neoplasms, cardiovascular disease, hypertension, hyperlipidemia, chronic liver disease, and chronic kidney disease as well as use of concomitant medications, including thiazide, beta blocking agents, statins, and corticosteroids
- T2DM type 2 diabetes mellitus, HR hazard ratio, CI confidence interval, PPI Proton pump inhibitor
