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Table 4 Joint association of non-traditional CVRF and BMI with MetS

From: Associations of non-traditional cardiovascular risk factors and body mass index with metabolic syndrome in the Chinese elderly population

  

Unadjusted model

Adjusted model

 

OR(95%CI)

P-value

OR(95%CI)

P-value

Non-HUA

Underweight

0.527(0.338–0.822)

0.005

0.472(0.274–0.811)

0.007

 

Normal weight

1.000 [ref.]

 

1.000 [ref.]

 
 

Overweight

2.768(2.385–3.212)

< 0.001

2.938(2.453–3.520)

< 0.001

 

Obese

5.130(4.098–6.422)

< 0.001

4.931(3.765–6.457)

< 0.001

HUA

Underweight

4.243(1.324–13.595)

0.015

4.753(1.344–16.811)

0.016

 

Normal weight

1.281(0.940–1.745)

0.117

1.392(0.956–2.026)

0.084

 

Overweight

3.746(2.845–4.931)

< 0.001

5.860(4.059–8.461)

< 0.001

 

Obese

6.001(3.892–9.252)

< 0.001

6.148(3.707–10.194)

< 0.001

Non-HHCY

Underweight

0.780(0.463–1.316)

0.352

0.690(0.362–1.314)

0.259

 

Normal weight

1.000 [ref.]

 

1.000 [ref.]

 
 

Overweight

2.993(2.470–3.628)

< 0.001

3.014(2.398–3.789)

< 0.001

 

Obese

5.366(4.024–7.155)

< 0.001

5.221(3.706–7.356)

< 0.001

HHCY

Underweight

0.594(0.325–1.086)

0.091

0.703(0.346–1.430)

0.331

 

Normal weight

1.072(0.877–1.310)

0.498

1.258(0.977–1.620)

0.075

 

Overweight

2.817(2.323–3.416)

< 0.001

3.989(3.107–5.121)

< 0.001

 

Obese

5.235(3.929–6.975)

< 0.001

5.746(4.064–8.123)

< 0.001

Non-HHsCRP

Underweight

0.626(0.396–0.990)

0.045

0.595(0.338–1.047)

0.072

 

Normal weight

1.000 [ref.]

 

1.000 [ref.]

 
 

Overweight

2.560(2.195–2.985)

< 0.001

2.931(2.429–3.537)

< 0.001

 

Obese

4.592(3.657–5.767)

< 0.001

4.399(3.357–5.765)

< 0.001

HHsCRP

Underweight

1.067(0.377–3.015)

0.903

1.288(0.409–4.059)

0.665

 

Normal weight

1.096(0.816–1.471)

0.542

1.271(0.901–1.793)

0.172

 

Overweight

3.876(2.960–5.075)

< 0.001

4.026(2.906–5.580)

< 0.001

 

Obese

6.578(4.257–10.162)

< 0.001

7.717(4.508–13.210)

< 0.001

  1. Note: Adjusted for age group, gender, occupation, education, monthly income, current smoking, current drinking, physical activity, ASCVD, liver, kidney, and thyroid dysfunction
  2. Considering ordinal BMI, interactions of abnormal status of non-traditional CVRF and BMI were more interested. Additive interaction RERI(95%CI): HUA + abnormal BMI: 2.521(0.793–4.250); HHCY + abnormal BMI: 0.589(-0.182-1.360); HHsCRP + abnormal BMI: 1.255(0.028–2.483). Multiplicative interaction OR(95%CI): HUA * abnormal BMI: 1.408(0.881–2.250); HHCY * abnormal BMI: 1.002(0.734–1.368); HHsCRP * abnormal BMI: 1.187(0.767–1.837)
  3. Abbreviations: CVRF, cardiovascular risk factors; MetS, metabolic syndrome; BMI, body mass index; UA, uric acid; HUA, hyperuricemia; HCY, homocysteine; HHCY, hyperhomocysteinemia; HHsCRP, high hypersensitive C-reactive protein; ASCVD, arteriosclerotic cardiovascular disease; RERI, relative excess risk due to interaction; OR, odds ratio; CI, confidence interval
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Diabetology & Metabolic Syndrome

ISSN: 1758-5996

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