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Table 2 DM characteristics among the studied cases and comparison according to the presence of NAFLD

From: Clinical and diagnostic characteristics of non-alcoholic fatty liver disease among Egyptian children and adolescents with type1 diabetes

Variables

All cases (N = 74)

NAFLD

P-value

Present (N = 46)

Absent (N = 28)

Age of onset (years), mean ± SD

8.0 ± 3.2

8.7 ± 3.0

6.8 ± 3.2

^0.015*

Duration (years), mean ± SD

6.3 ± 3.0

6.7 ± 3.2

5.6 ± 2.4

^0.110

Insulin dose (unit/kg/day) Mean ± SD

1.1 ± 0.4

1.1 ± 0.4

1.1 ± 0.3

^0.520

History of DKA (n, %)

70 (94.6%)

45 (97.8%)

25 (89.3%)

§0.149

DKA frequency (attack/duration), mean ± SD

0.7 ± 0.6

0.7 ± 0.5

0.6 ± 0.6

^0.458

Complications, (n, %)

Total cases with complications

48 (64.9%)

35 (76.1%)

13 (46.4%)

#0.010*

Lipodystrophy

25 (33.8%)

20 (43.5%)

5 (17.9%)

#0.024*

Joint affection

25 (33.8%)

19 (41.3%)

6 (21.4%)

#0.080

Neuropathy

22 (29.7%)

18 (39.1%)

4 (14.3%)

#0.023*

Nephropathy

7 (9.5%)

6 (13.0%)

1 (3.6%)

§0.242

Symptoms of liver affection, (n, %)

Total cases with symptoms

51 (68.9%)

37 (80.4%)

14 (50.0%)

#0.006*

Abdominal pain

45 (60.8%)

33 (71.7%)

12 (42.9%)

#0.014*

Nausea

30 (40.5%)

24 (52.2%)

6 (21.4%)

#0.009*

Vomiting

24 (32.4%)

19 (41.3%)

5 (17.9%)

#0.037*

Pruritis

10 (13.5%)

7 (15.2%)

3 (10.7%)

§0.733

Jaundice

0 (0.0%)

0 (0.0%)

0 (0.0%)

Not applicable

  1. ^Independent t-test
  2. #Chi square test
  3. §Fishers exact test
  4. *Significant (p < 0.050)