Table 1 Features of the study population according to current antidepressant use
Non-antidepressant use | Antidepressant use | P-value | |
|---|---|---|---|
N | 612 | 142 | |
Age(years) | 61.9 ± 13.0 | 61.5 ± 13.4 | 0.806 |
Male(%) | 359 (58.7%) | 55 (38.7%) | < 0.001 |
Race/ethnicity (%) | < 0.001 | ||
Non-Hispanic white | 171 (27.9%) | 69 (48.6%) | |
Non-Hispanic Black | 135 (22.1%) | 34 (23.9%) | |
Mexican American | 102 (16.7%) | 11 (7.7%) | |
other | 204 (33.3%) | 28 (19.7%) | |
BMI(kg/m2) | 31.8 ± 7.5 | 33.6 ± 7.4 | 0.003 |
Waist circumference (cm) | 107.9 ± 16.2 | 111.4 ± 15.5 | 0.02 |
Laboratory variables | |||
ALT(IU/L) | 24.5 ± 17.5 | 19.2 ± 9.9 | < 0.001 |
AST(IU/L) | 22.6 ± 14.2 | 19.7 ± 8.0 | 0.009 |
Albumin(g/L) | 40.1 ± 3.1 | 38.7 ± 4.0 | < 0.001 |
GGT(IU/L) | 39.9 ± 48.4 | 34.7 ± 46.4 | 0.015 |
HDL(mg/dL) | 48.7 ± 13.6 | 49.0 ± 14.6 | 0.965 |
LDL(mg/dl) | 2.87 ± 0.04 | 2.73 ± 0.06 | 0.05 |
Total cholesterol (mg/dL) | 179.4 ± 45.0 | 172.4 ± 45.8 | 0.019 |
Triglycerides (mg/dL) | 135.0 ± 116.3 | 174.6 ± 178.2 | 0.032 |
HbA1c (%) | 7.2 ± 1.6 | 7.1 ± 1.4 | 0.271 |
LSM(kPa) | 7.2 ± 5.9 | 7.5 ± 9.0 | 0.391 |
CAP(dB/m) | 302.1 ± 55.9 | 304.3 ± 55.7 | 0.752 |
Fibrosis≧2 | 139 (22.7%) | 26 (18.3%) | 0.253 |
Fibrosis≧4 | 43 (7.0%) | 8 (5.6%) | 0.552 |
Steatosis≧1 | 411 (67.2%) | 99 (69.7%) | 0.557 |
Steatosis≧3 | 315 (51.5%) | 73 (51.4%) | 0.989 |