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Table 1 Demographic characteristics of the study population

From: Association of triglyceride-glucose index with atherosclerotic cardiovascular disease and mortality among familial hypercholesterolemia patients

 

TyG < 8.5 (N = 204)

TyG 8.5–9 (N = 311)

TyG > 9 (N = 426)

p value

Age (SD) (y.o.)

50.0 (15.5)

50.6 (16.0)

53.6 (14.4)

0.004

Female (%)

125 (61.3%)

164 (52.7%)

241 (56.6%)

0.159

Race (%)

   

 < 0.001

 White

89 (43.6%)

163 (52.4%)

228 (53.5%)

 

 Black

64 (31.4%)

62 (19.9%)

57 (13.4%)

 

 Mexican American

13 (6.37%)

40 (12.9%)

70 (16.4%)

 

 Other

38 (18.6%)

46 (14.8%)

71 (16.7%)

 

 BMI (SD) (kg/m2)

28.6 (7.37)

29.3 (6.31)

30.4 (6.60)

0.004

 Poverty ratio (SD)

2.46 (1.65)

2.29 (1.56)

2.34 (1.55)

0.504

 DLCN score (SD)

3.51 (0.79)

3.57 (0.84)

3.61 (0.99)

0.397

DM status (%)

   

 < 0.001

 DM

16 (7.92%)

38 (12.8%)

159 (39.2%)

 

 IFG

12 (5.94%)

32 (10.7%)

55 (13.5%)

 

 IGT

11 (5.45%)

26 (8.72%)

27 (6.65%)

 

 No

163 (80.7%)

202 (67.8%)

165 (40.6%)

 

Education status (%)

   

0.005

 College or above

108 (53.2%)

147 (47.4%)

165 (38.9%)

 

 High school or equivalent

50 (24.6%)

72 (23.2%)

111 (26.2%)

 

 Less than high school

45 (22.2%)

91 (29.4%)

148 (34.9%)

 

 Drink (%)

132 (64.7%)

187 (60.1%)

235 (55.2%)

0.064

 Smoke (%)

107 (52.7%)

176 (57.5%)

246 (57.7%)

0.748

 ASCVD (%)

59 (29.1%)

89 (29.1%)

146 (34.4%)

0.126

 Hypertension (%)

98 (48.0%)

145 (46.6%)

223 (52.3%)

0.275

 SBP (SD) (mmHg)

126 (23.0)

125 (19.3)

129 (20.7)

0.025

 DBP (SD) (mmHg)

71.8 (13.0)

70.7 (12.6)

72.1 (13.6)

0.388

 HbA1c (SD) (%)

5.5 (0.5)

5.7 (0.7)

6.5 (2.0)

 < 0.001

 Fasting insulin (μU/mL)

9.15 (6.45)

13.9 (28.7)

16.6 (17.3)

 < 0.001

Fasting glucose (SD) (mmol/L)

5.35 (0.66)

5.59 (0.93)

7.32 (3.56)

 < 0.001

 HOMA-IR index (SD)

2.22 (1.70)

3.52 (7.29)

5.61 (8.81)

 < 0.001

 ALT (SD) (U/L)

23.9 (15.7)

26.8 (27.0)

34.2 (96.5)

0.139

 AST (SD) (U/L)

26.4 (21.6)

26.8 (31.2)

27.0 (18.7)

0.952

 Creatinine (SD) (μmol/L)

76.1 (22.3)

75.8 (26.3)

77.8 (32.4)

0.593

 Fasting TG (SD) (mg/dL)

79.3 (18.6)

128 (24.9)

216 (72.1)

 < 0.001

 Fasting TC (SD) (mg/dL)

255 (56.5)

262 (53.0)

280 (60.6)

 < 0.001

 HDL-C (SD) (mg/dL)

61.2 (17.9)

52.3 (13.6)

47.9 (13.7)

 < 0.001

 LDL-C (SD) (mg/dL)

178 (53.3)

184 (49.0)

190 (55.7)

0.038

  1. TyG, triglyceride-glucose index; SD, standard deviation; BMI, body mass index; DLCN, Dutch Lipid Clinical Network; DM, diabetes mellitus; IFG, impaired fasting blood glucose; IGT, impaired glucose tolerance; ASCVD, atherosclerotic cardiovascular diseases; DBP, diastolic blood pressure; SBP, systolic blood pressure; ALT, alanine aminotransferase; AST, aspartate aminotransferase; TG, total glyceride; TC, total cholesterol; HDL-C, high density lipoprotein cholesterol; LDL-C, low density lipoprotein cholesterol