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Table 3 Hazard ratios and 95% confidence intervals for incident metabolic syndrome by GGT quartiles in men and women

From: Serum γ-glutamyltransferase level and incidence risk of metabolic syndrome in community dwelling adults: longitudinal findings over 12 years

 

GGT quartiles in men

GGT quartiles in women

 

Q1 (≤ 17)

Q2 (18–27)

Q3 (28–47)

Q4 (≥ 48)

Q1 (≤ 9)

Q2 (10–12)

Q3 (13–16)

Q4(≥ 17)

Total, n

803

762

797

765

752

775

622

681

New cases of type 2 diabetes, n

208

270

334

403

279

319

280

385

Mean follow-up (years)

8.7 (3.6)

8.5 (3.6)

7.7 (3.6)

6.9 (3.6)

8.3 (3.9)

7.8 (4.0)

7.6 (4.1)

6.6 (4.0)

Person-years of follow-up

6989

6513

6143

5298

6265

6054

4758

4488

Incidence rate per 1000 person-year

29.8

41.5

54.4

76.1

44.5

52.7

58.8

85.8

Model 1

1.00 (ref)

1.22 (0.94–1.58)

2.01 (1.59–2.54)

3.05 (2.33–3.73)

1.00 (ref)

1.15 (0.81–1.63)

1.17 (0.83–1.65)

1.76 (1.27–2.43)

Model 2

1.00 (ref)

1.21 (0.94–1.58)

2.00 (1.58–2.54)

3.04 (2.32–3.71)

1.00 (ref)

1.13 (0.79–1.60)

1.17 (0.83–1.64)

1.72 (1.24–2.39)

Model 3

1.00 (ref)

1.21 (0.94–1.58)

2.03 (1.60–2.58)

3.01 (2.35–3.76)

1.00 (ref)

1.10 (0.77–1.58)

1.11 (0.78–1.57)

1.83 (1.30–2.57)

  1. Model 1: adjusted for age, smoking status, daily alcohol intake (g/day), and regular exercise
  2. Model 2: adjusted for age, smoking status, daily alcohol intake (g/day), regular exercise, and family history of diabetes
  3. Model 3: adjusted for age, smoking status, daily alcohol intake (g/day), regular exercise, family history of diabetes, and log-transformed LDL-cholesterol, creatinine, and aminotransferase levels