Niclosamide arm n = 30 | Control arm n = 30 | P value between arms | |
---|---|---|---|
UACR (mg/g) | |||
Baseline | 225.5 ± 83 | 247.7 ± 80 | 0.299 |
After 6 months | 170.9 ± 72 | 271.3 ± 86.6 | < 0.0001* |
Percent change between the 2 points | − 24.2 ± 15 | 11.1 ± 19 | < 0.0001* |
P Value within each arm | < 0.0001* | 0.005* | |
Serum creatinine (mg/dL) | |||
Baseline | 1.1 ± 0.13 | ± 0.31.1 | 0.503 |
After 6 months | 1.08 ± 0.09 | 1.2 ± 0.2 | 0.069* |
Percent change between the 2 points | − 1 ± 8.2 | 5 ± 9.6 | 0.017* |
P Value within each arm | 0.245 | 0.014* | |
eGFR (mL/min/1.73 m2) | |||
Baseline | 84.7 ± 15 | 81.9 ± 18.7 | 0.528 |
After 6 months | 85.4 ± 13.8 | 78 ± 14.1 | 0.040* |
Percent change between the 2 points | 1.5 ± 7.7 | − 3.5 ± 8.8 | 0.029* |
P Value within each arm | 0.583 | 0.02* |