Table 1 The DALYs of NASH related liver cancer attributable to HFPG in 1990 and 2019, and its temporal trends from 1990 to 2019
Characteristics | 1990 | 2019 | 1990–2019 | ||||
|---|---|---|---|---|---|---|---|
DALYs cases No. (95% UI) | ASR per 1000 No. (95% UI) | Percentage (%) | DALYs cases No. (95% UI) | ASR per 100,000 No. (95% UI) | Percentage (%) | EAPC No. (95% CI) | |
Overall | 22,814.15 (5224.6–51,824.35) | 0.57 (0.13–1.31) | 4.77 (1.1–10.38) | 60,308.72 (14,610.29–135,326.46) | 0.73 (0.18–1.65) | 7.59 (1.8–16.02) | 0.3 (0.05–0.56) |
Socio-demographic index | |||||||
High SDI | 3728.39 (884.31–8399.56) | 0.35 (0.08–0.8) | 6.18 (1.42–13.24) | 15,009.74 (3683.96–33,421.49) | 0.80 (0.2–1.78) | 9.74 (2.39–20.18) | 2.87 (2.62–3.11) |
High-middle SDI | 6188.13 (1408.76–14,086.36) | 0.57 (0.13–1.3) | 4.98 (1.13–10.86) | 9880.89 (2385.02–22,226.78) | 0.48 (0.12–1.08) | 7.22 (1.69–15.29) | –1.39 (–1.73––1.05) |
Middle SDI | 9473.12 (2117.33–21,730.86) | 0.93 (0.21–2.11) | 4.46 (1.03–9.71) | 23,847.28 (5768.12–54,084.87) | 0.96 (0.23–2.18) | 7.18 (1.69–15.15) | –0.61 (–1.05––0.16) |
Low-middle SDI | 2573.91 (593.05–5825.6) | 0.45 (0.1–1.01) | 4.27 (0.98–9.29) | 8734.82 (2070.69–19,802.48) | 0.65 (0.16–1.48) | 7.2 (1.7–15.1) | 0.81 (0.6–1.03) |
Low SDI | 837.44 (192.22–2036.17) | 0.38 (0.09–0.92) | 3.88 (0.88–8.51) | 2800.07 (647.08–6650.46) | 0.57 (0.14–1.34) | 5.64 (1.33–11.87) | 1.24 (1.16–1.33) |
Region | |||||||
Andean Latin America | 79.78 (16.55–199.66) | 0.42 (0.09–1.06) | 4.11 (0.86–9.2) | 305.12 (66.59–748.71) | 0.56 (0.12–1.38) | 7.81 (1.67–16.73) | 0.68 (0.33–1.03) |
Australasia | 31.55 (6.75–77.81) | 0.13 (0.03–0.32) | 3.92 (0.87–8.62) | 304.66 (68.48–717.36) | 0.61 (0.14–1.44) | 6.94 (1.59–14.89) | 5.5 (5.07–5.93) |
Caribbean | 247.02 (56.82–591.37) | 0.96 (0.22–2.28) | 8.01 (1.85–16.63) | 362.26 (88.96–865.62) | 0.7 (0.17–1.67) | 10.29 (2.49–21.13) | –0.92 (–1.79––0.04) |
Central Asia | 69.69 (15.19–179.59) | 0.15 (0.03–0.4) | 3.45 (0.74–7.58) | 666.45 (146.5–1639.07) | 0.94 (0.21–2.28) | 5.97 (1.34–12.74) | 5.71 (5.07–6.34) |
Central Europe | 820.92 (186.76–1900.68) | 0.55 (0.13–1.27) | 6.49 (1.44–13.92) | 1136.53 (272.8–2739.61) | 0.52 (0.12–1.24) | 9.8 (2.35–20.21) | 0.09 (–0.37–0.55) |
Central Latin America | 435.56 (102.98–1004.28) | 0.55 (0.13–1.27) | 7.79 (1.83–16.11) | 2033.89 (499.42–4618.83) | 0.88 (0.22–1.97) | 11.7 (2.87–23.56) | 1.73 (1.49–1.97) |
Central Sub-Saharan Africa | 43.87 (9.12–113.7) | 0.21 (0.04–0.52) | 3.84 (0.85–8.46) | 140.87 (29.16–362.18) | 0.28 (0.06–0.69) | 5.06 (1.14–10.83) | 0.8 (0.71–0.9) |
East Asia | 11,760.54 (2615.07–27,185.61) | 1.3 (0.29–2.99) | 4.47 (1.02–9.71) | 14,381.59 (3385.91–32,233.35) | 0.68 (0.16–1.52) | 6.05 (1.37–13.15) | –3.72 (–4.39––3.04) |
Eastern Europe | 238.55 (52.46–548.58) | 0.08 (0.02–0.2) | 3.38 (0.73–7.39) | 835.38 (192.14–1940.18) | 0.24 (0.06–0.55) | 4.78 (1.04–10.45) | 4.19 (3.92–4.45) |
Eastern Sub-Saharan Africa | 214.5 (47.29–534.27) | 0.31 (0.07–0.77) | 3.2 (0.72–7.09) | 718.23 (157.7–1750.77) | 0.48 (0.11–1.18) | 4.16 (0.94–9) | 1.35 (1.2–1.5) |
High-income Asia Pacific | 1239.46 (288.87–2772.63) | 0.6 (0.14–1.34) | 5.41 (1.23–11.74) | 3131.43 (737.54–7239.83) | 0.69 (0.16–1.62) | 7.41 (1.72–16.08) | –0.34 (–0.97–0.29) |
High-income North America | 1137.48 (267.93–2483.84) | 0.32 (0.08–0.69) | 7.72 (1.83–16.2) | 6915.45 (1756.89–14,784.65) | 1.1 (0.28–2.36) | 11.82 (2.94–24.03) | 5.54 (5.13–5.96) |
North Africa and Middle East | 1043.71 (230.45–2623.78) | 0.64 (0.14–1.59) | 4.7 (1.08–10.3) | 6237.91 (1407.41–14,658.2) | 1.48 (0.34–3.48) | 8.88 (2.18–18.68) | 3.41 (3.18–3.63) |
Oceania | 17.22 (3.82–44.07) | 0.61 (0.14–1.55) | 7.52 (1.82–15.97) | 67.6 (16.83–155.11) | 1 (0.26–2.32) | 12.6 (3.37–25.29) | 1.82 (1.65–1.98) |
South Asia | 1801.6 (411.07–4093.7) | 0.34 (0.08–0.77) | 4.51 (1.04–9.79) | 8282.17 (2018.13–18,376.16) | 0.6 (0.15–1.33) | 7.93 (1.93–16.45) | 1.77 (1.65–1.9) |
Southeast Asia | 1388.78 (310.64–3365.4) | 0.59 (0.13–1.4) | 4.08 (0.93–8.91) | 7014.6 (1670.42–16,599.05) | 1.25 (0.3–3.01) | 7.3 (1.71–15.54) | 2.52 (2.43–2.62) |
Southern Latin America | 68.64 (14.72–173.19) | 0.15 (0.03–0.37) | 5.55 (1.22–11.94) | 369.12 (86.57–867.65) | 0.44 (0.1–1.02) | 9.51 (2.26–19.73) | 4.44 (4.25–4.64) |
Southern Sub-Saharan Africa | 216.97 (45.54–590.34) | 0.83 (0.17–2.24) | 4.3 (1–9.35) | 831.04 (201.54–1831.98) | 1.52 (0.37–3.35) | 7.02 (1.67–14.79) | 1.72 (1.08–2.36) |
Tropical Latin America | 161.53 (38.59–355.11) | 0.18 (0.04–0.4) | 5.85 (1.35–12.46) | 673.33 (161.98–1460.64) | 0.28 (0.07–0.61) | 7.76 (1.83–16.27) | 2.18 (1.87–2.5) |
Western Europe | 1475.54 (334.91–3417.45) | 0.25 (0.06–0.57) | 6.65 (1.54–14.2) | 4823.89 (1145.08–11,045.46) | 0.53 (0.13–1.21) | 9.9 (2.36–20.64) | 2.65 (2.45–2.85) |
Western Sub-Saharan Africa | 321.24 (70.59–783.6) | 0.4 (0.09–0.97) | 3.35 (0.77–7.42) | 1077.22 (236.93–2607.65) | 0.65 (0.15–1.54) | 4.92 (1.15–10.62) | 1.47 (1.34–1.59) |