Effectiveness and safety of a model predictive control (MPC) algorithm for an artificial pancreas system in outpatients with type 1 diabetes (T1D): systematic review and meta-analysis

Kang, Su Lim; Hwang, Yoo Na; Kwon, Ji Yean; Kim, Sung Min

doi:10.1186/s13098-022-00962-2

Table 1 Characteristics of the included studies

From: Effectiveness and safety of a model predictive control (MPC) algorithm for an artificial pancreas system in outpatients with type 1 diabetes (T1D): systematic review and meta-analysis

No	Study	Year	Patients	Intervention	Algorithm	Comparator	Duration	Follow-up
1	Anderson et al. [24]	2019	42	DiAs USS with Dexcom	MPC	SAP	24 h	4 weeks
2	Bally et al. [25]	2017	29	Florence with freestyle navigator	MPC	SAP	24 h	4 weeks
3	Benhamou et al. [26]	2019	63	Hybrid closed-loop system	MPC	SAP	24 h	12 weeks
4	Blauw et al. [27]	2016	10	Inreda diabetic	PID	Pump	24 h	4 days
5	Breton et al. [28]	2020	101	t:slim X2 insulin pump, Dexcom with Control-IQ Technology	MPC	SAP	24 h	16 weeks
6	Breton et al. 2 [29]	2017	32	t:AP pump or Roche Accu-Chek Spirit Combo pump, Dexcom with DiAs	MPC	SAP	24 h	120 h
7	Brown et al. [30]	2019	168	t:slim X2 insulin pump with Control-IQ Technology, Tandem Diabetes Care, Dexcom	MPC	SAP	24 h	6 months
8	Brown et al. 2 [31]	2017	40	DiAs USS with Dexcom	MPC	SAP	Overnight	5 days
9	Brown et al. 3 [32]	2015	10	Accu-Chek Spirit Combo pump or personal pump, Dexcom with DiAs system	PID	SAP	Overnight	5 days
10	Chernavvsky et al. [33]	2016	16	DiAs USS with Dexcom	MPC	Pump	24 h	1 day
11	De bock et al. [34]	2018	12	Medtronic MiniMed Hybrid Closed Loop System	MPC	Pump	24 h	7 days
12	De boer et al. [35]	2017	12	DiAs USS with Dexcom	MPC	SAP	24 h	3 days
13	Del Favero et al. [36]	2016	30	Accu-Chek Spirit Combo pump or personal pump, Dexcom with DiAs system	MPC	SAP	24 h	72 h
14	El-Khatib et al. [37]	2017	39	Two(one for insulin, one for glucagon) t:Slim infusion pumps, Dexcom	MPC	Pump	24 h	11 days
15	Elleri et al. [38]	2013	12	SEVEN PLUS; Dexcom	MPC	Pump	Overnight	36 h
16	Forlenza et al. [39]	2017	19	DiAs	MPC	SAP	24 h	2 weeks
17	Forlenza et al. 2 [40]	2017	28	Medtronic PHHM	MPC	SAP	Overnight	21 nights
18	Haidar et al. [20]	2021	36	Dexcom CGM system, t:slim TAP3 insulin pump	MPC	SAP	24 h	12 days
19	Hovorka et al. [41]	2014	16	Florence with FreeStyle Navigator	MPC	SAP	Overnight	21 days
20	Huyett et al. [42]	2017	10	DiAs with Dexcom	MPC	SAP	24 h	72 h
21	Kovatchev et al. [43]	2020	125	Accu-Chek Spirit Combo insulin pump, Dexcom CGM system, and inControlAP	MPC	SAP	Overnight	3 months
22	Kovatchev et al. 2 [44]	2020	78	Accu-Chek Spirit Combo insulin pump, Dexcom CGM system, and inControlAP	MPC	SAP	Overnight	10 months
23	Kovatchev et al. 3 [45]	2014	18	Tandem t:slim pump, with DiAs system	PID	SAP	24 h	40 h
24	Kropff et al. [46]	2015	32	Accu-Chek Spirit Combo insulin pump, Dexcom CGM system	MPC	SAP	Overnight	12 weeks
25	Leelarathna et al. [47]	2014	17	Florence with FreeStyle Navigator	MPC	SAP	24 h	8 days
26	Ly et al. [48]	2016	21	Medtronic MiniMed Hybrid Closed Loop System	PID	SAP	Overnight	5–6 days
27	Ly et al. 2 [49]	2015	21	Medtronic MiniMed Hybrid Closed Loop System	PID	SAP	24 h	6 days
28	Ly et al. 3 [50]	2014	20	Medtronic MiniMed Hybrid Closed Loop System	PID	SAP	Overnight	5–6 days
29	Nimri et al. [51]	2014	24	MD-Logic system with Medtronic Paradigm Veo pump	Fuzzy	SAP	Overnight	6 weeks
30	Nimri et al. 2 [52]	2014	15	MD-Logic system with Medtronic Paradigm Veo pump	Fuzzy	SAP	Overnight	4 days
31	Renard et al. [53]	2018	23	DiAs with Dexcom	MPC	SAP	24 h	2 days
32	Russell et al. [54]	2016	19	Two(one for insulin, one for glucagon) t:Slim infusion pumps, Dexcom	MPC	Pump	24 h	5 days
33	Russell et al. 2a [55]	2014	20	Two(one for insulin, one for glucagon) t:Slim infusion pumps, Dexcom	MPC	Pump	24 h	5 days
34	Russell et al. 2b [55]	2014	32	Two(one for insulin, one for glucagon) t:Slim infusion pumps, Dexcom	MPC	Pump	24 h	5 days
35	Sherr et al. [56]	2020	11	Omnipod hybrid closed loop system	MPC	Pump	Overnight	7 days
36	Spaic et al. [57]	2017	30	Medtronic PHHM	MPC	SAP	Overnight	21 nights
37	Tauschmann et al. [58]	2018	86	Medtronic hybrid closed loop system	MPC	SAP	24 h	12 weeks
38	Tauschmann et al. 2 [59]	2016	12	Florence with freestyle navigator	MPC	SAP	24 h	3 weeks
39	Tauschmann et al. 3 [60]	2016	12	Florence with freestyle navigator	MPC	SAP	24 h	7 days
40	Thabit et al. [61]	2015	33	Florence with freestyle navigator	MPC	SAP	24 h	12 weeks
41	Thabit et al. 2 [62]	2014	24	Florence with freestyle navigator	MPC	SAP	Overnight	4 weeks

MPC Model Predictive Control, PID Proportional Integral Derivative, SAP Sensor-Augmented Pump, CGM Continuous Glucose Monitoring, DiAs Diabetes Assistant

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ISSN: 1758-5996

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