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Table 1 Demographic and clinical characteristics of patients at admission

From: Predictive markers for clinical outcomes in a cohort of diabetic patients hospitalized for COVID-19

Variable

Overall cohort

(n = 291)

Age (years)

72 (63–79)

Male sex

210 (72.2%)

Type of diabetes

 Type 2

277 (95.2%)

 Type 1

7 (2.4%)

 Secondary diabetes

7 (2.4%)

 Diabetes duration (years)

16 (1–51)

 BMI (kg/m2)

28.6 (26.3–32.9)

 History of tobacco use

93 (31.9%)

Comorbidities

 Hypertension

126 (43.3%)

 Chronic kidney disease

122 (42.2%)

 Coronary artery disease

80 (27.4%)

 Diabetic foot

26 (8.9%)

 Retinopathy

52 (17.8%)

 Neuropathy

20 (6.9%)

 Malignancy

20 (6.9%)

Laboratory data

 Glucose (mg/dl)

152.5 (108–199)

 HbA1c (mmol/mol)

66 (58–79)

 HbA1c (%)

8.2 (7.5–9.4)

 Platelets count (PLT 103/μL)

229,500 (161,000–331,000)

 White blood cell count (WBC 103/μL l)

7.32 (5.53–10.22)

 Absolute basophil count (103/μL)

0.02 (0.43–0.84)

 Absolute lymphocyte count (103/ μL)

1.22 (0.75–1.68)

 Absolute eosinophils count (103/μL)

0.08 (0.010–0.17)

 Absolute neutrophil count (103/μL)

4.98 (3.41–8.11)

 Absolute monocyte count (103/μL)

8.4 (5.3–10.5)

 CRP (mg/l)

16 (4.3–56.8)

 Fibrinogen (mg/dl)

443 (335–558)

 D-Dimer (ng/ml)

514 (294–1208)

 Ferritin (μg/l)

594 (291–1087)

 Procalcitonin (ng/ml)

0.20 (0.10–0.49)

 NLR

4.06 (2.25–8.92)

 LDH (U/l)

276 (223–365)

 Creatinine (mg/dl)

1.04 (0.8–1.6)

eGFR CDK-EPI (ml/min × 1.73 m2)

  ≤ 30

48 (16.6%)

 30–75

112 (38.7%)

  > 75

129 (44.6%)

Outcomes

 In hospital death

74 (25%)

 Need of oxygen supplementation

151 (51.9%)

 Intensive care unit

20 (6.9%)

 Length of hospitalization (days)

14 (8–23)

Therapy during hospitalization

 Steoroids

151 (57.4%)

 Hydroxyclorochine

149 (56.6%)

 Antiretrovirals

148 (56.2%)

 Tocilizumab/kanakinumab

17 (6.6%)

 Antibiotics

216 (82.4%)

 Insulin

142 (53.9%)

  1. Continuous variables are summarized as median and interquartile range (IQR); categorical variables as number and percentage of patients
  2. BMI Body Mass Index, HbA1c Glycated Haemoglobin, CRP C-Reactive Protein, NLR Neutrophil-to-Lymphocyte Ratio, LDH Lactate Dehydrogenase, eGFR Estimated Glomerular Filtration Rate, CDK-EPI Chronic Kidney Disease Epidemiology Collaboration