Fig. 6From: Effect of plasma-derived extracellular vesicles on angiogenesis and the ensuing proliferative diabetic retinopathy through a miR-30b-dependent mechanism Schematic diagram of the mechanism by which miR-30b shuttled by plasma-EVs affects angiogenesis and PDR progression. Plasma-EVs deliver miR-30b to RMECs where miR-30b targets SIRT1 and inhibits its expression, upregulating VEGF expression and inducing angiogenesis, thereby promoting the occurrence of PDRBack to article page