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Fig. 1 | Diabetology & Metabolic Syndrome

Fig. 1

From: Effect of plasma-derived extracellular vesicles on angiogenesis and the ensuing proliferative diabetic retinopathy through a miR-30b-dependent mechanism

Fig. 1

Robustly induced miR-30b in the retinal tissue of PDR mice. A A heat map of the expression of significantly differentially expressed miRNAs from PDR-related dataset GSE140959. The color scale from green to red indicates the expression value from small to large. B miR-30b expression in the PDR (n = 11) and control samples (n = 10). C Body weight and blood glucose level of control and PDR mice at the 8th week. D, Total retinal thickness in the circular area of control and PDR mouse optic nerve head determined by OCT. E H&E staining analysis of the retinal thickness of control and PDR mice (25 μm). F Statistics of the number of acellular capillaries in the retinal tissues of control and PDR mice. G Statistics of the number of pericytes in the retinal tissues of control and PDR mice. H Expression of miR-30b determined by RT-qPCR in the retinal tissues of control and PDR mice. *p < 0.05, compared with the control mice. n = 6 for control and PDR mice

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Diabetology & Metabolic Syndrome

ISSN: 1758-5996

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