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Fig. 3 | Diabetology & Metabolic Syndrome

Fig. 3

From: Targeting hepatic sulfane sulfur/hydrogen sulfide signaling pathway with α-lipoic acid to prevent diabetes-induced liver injury via upregulating hepatic CSE/3-MST expression

Fig. 3

Liver histology, parameters of liver function and lipid profile A Representative photomicrographs of hematoxylin and eosin, and oil red O staining at 400 × and 100 × magnification respectively. Yellow arrows in HE images point to hepatocellular vacuolation and sinusoidal enlargement while red stains in oil red O images indicate triglyceride and other lipid accumulation. B and C Quantification of liver histology, D ALT, E AST, F ALP, G total bilirubin, H plasma triglyceride, I hepatic triglyceride, I plasma triglyceride, J plasma total cholesterol, K hepatic total cholesterol, L plasma FFA, M hepatic FFA, N plasma LDL and O plasma HDL. HC = Healthy control; T2DM = Untreated diabetic control; T2DM + ALA = Diabetic rats treated with alpha-lipoic acid; DT2M + PPG = Diabetic rats treated with propargylglycine

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Diabetology & Metabolic Syndrome

ISSN: 1758-5996

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