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Table 6 Comparison of the clinical and biochemical data stratified by CD36 gene methylation in the control, obese and obese diabetic groups

From: Association between polymorphisms and hypermethylation of CD36 gene in obese and obese diabetic Senegalese females

Variables

Control

Obese

Obese diabetic

Unmethylated

Methylated

p value

Unmethylated

Methylated

p value

Unmethylated

Methylated

p value

Body mass index (kg/m2)

24.31 ± 2.64

23.94 ± 2.97

NS

34.97 ± 5.51

33.69 ± 3.59

NS

32.63 ± 3.27

33.78 ± 4.95

NS

Waist size (cm)

83.44 ± 8.94

83.21 ± 9.97

NS

103.05 ± 9.03

102.52 ± 10.13

NS

102.86 ± 10.71

100.56 ± 12.63

NS

Percent body fat (%)

38.34 ± 6.42

36.23 ± 6.04

NS

45.54 ± 4.55

45.82 ± 4.04

NS

44.39 ± 4.71

45.39 ± 4.71

NS

Visceral fat level

7.12 ± 1.59

6.50 ± 1.83

NS

11.53 ± 2.09

11.50 ± 2.15

NS

10.81 ± 1.97

11.56 ± 2.59

NS

Fasting blood glucose (g/l)

0.88 ± 0.12

0.80 ± 0.12

NS

0.88 ± 0.24

0.87 ± 0.26

NS

1.74 ± 0.82

1.45 ± 0.74

NS

Glycated hemoglobin (%)

5.03 ± 0.57

4.92 ± 0.68

NS

5.50 ± 0.70

5.61 ± 0.70

NS

8.31 ± 2.13

7.64 ± 2.02

NS

IR-HOMA

3.80 ± 1.85

3.22 ± 1.64

NS

5.23 ± 2.33

4.57 ± 1.93

NS

9.28 ± 11.65

7.06 ± 10.88

NS

Total cholesterol (g/l)

2.10 ± 0.46

2.19 ± 0.48

NS

2.07 ± 0.35

2.14 ± 0.44

NS

2.14 ± 0.50

2.35 ± 0.60

NS

HDL cholesterol (g/l)

0.62 ± 0.14

0.63 ± 0.13

NS

0.57 ± 0.15

0.60 ± 0.13

NS

0.57 ± 0.17

0.58 ± 0.15

NS

LDL cholesterol (g/l)

1.35 ± 0.37

1.45 ± 0.41

NS

1.38 ± 0.31

1.42 ± 0.43

NS

1.55 ± 0.39

1.71 ± 0.62

0.01**

Triglycerides (g/l)

0.86 ± 0.31

0.65 ± 0.25

NS

0.82 ± 0.31

0.75 ± 0.35

NS

0.83 ± 0.43

0.89 ± 0.33

NS

  1. HOMA-IR Homeostasis Model Assessment-Insulin Resistance
  2. *: p ≤ 0.05
  3. **: p ≤ 0.01
  4. ***: p ≤ 0.0001