Table 6 Top twenty overrepresented biological process
Term | Count | p-value | Gene symbol |
|---|---|---|---|
Positive regulation of glucose import | 5 | 1.70E−09 | AKT2, IRS1, IRS2, MAPK14, PIK3R1 |
Glucose metabolic process | 4 | 7.10E−06 | AKT2, G6PD, IRS2, MAPK14, |
Cellular response to insulin stimulus | 4 | 1.10E−05 | AKT2, IRS1, IRS2, PIK3R1 |
Insulin receptor signaling pathway | 4 | 1.10E−05 | AKT2, IRS1, IRS2, PIK3R1 |
Positive regulation of fatty acid beta-oxidation | 3 | 1.10E−05 | AKT2, IRS1, IRS2 |
Positive regulation of glucose metabolic process | 3 | 1.10E−05 | AKT2, IRS1, IRS2 |
Positive regulation of glucose import in response to insulin stimulus | 3 | 2.50E−05 | AKT2, IRS1, PIK3R1 |
Positive regulation of glycogen biosynthetic process | 3 | 3.30E−05 | AKT2, IRS1, IRS2 |
Cellular response to lipopolysaccharide | 4 | 3.40E−05 | IL12B, IL6, MAPK14, NFKB1 |
Signal transduction | 6 | 2.90E−04 | AKT2, IRS1, IRS2, MAPK14, NFKB1, PIK3R1 |
Phosphatidylinositol-3-phosphate biosynthetic process | 3 | 3.70E−04 | IRS1, IRS2, PIK3R1 |
Regulation of phosphatidylinositol 3-kinase signaling | 3 | 9.40E−04 | IRS1, IRS2, PIK3R1 |
Phosphatidylinositol phosphorylation | 3 | 1.40E−03 | IRS1, IRS2, PIK3R1 |
Phosphatidylinositol-mediated signaling | 3 | 1.70E−03 | IRS1, IRS2, PIK3R1 |
Positive regulation of transcription from RNA polymerase II promoter | 5 | 1.80E−03 | FOXP3, IL6, MAPK14, NFKB1, PIK3R1 |
Negative regulation of plasma membrane long-chain fatty acid transport | 2 | 2.40E−03 | AKT2, IRS2 |
T cell receptor signaling pathway | 3 | 3.30E−03 | FOXP3, NFKB1, PIK3R1 |
Positive regulation of cell migration | 3 | 5.10E−03 | AKT2, IRS2, PIK3R1 |
Negative regulation of interleukin-17 production | 2 | 6.50E−03 | FOXP3, IL12B |
Negative regulation of interleukin-10 production | 2 | 7.10E−03 | FOXP3, IL12B |