Oral glucose tolerance testing at 1 h and 2 h: relationship with glucose and cardiometabolic parameters and agreement for pre-diabetes diagnosis in patients with morbid obesity

Table 5 Comparison between 1 h post-load glucose < 155 vs ≥ 155 mg/dL in subjects with normal glucose tolerance (n = 295)

		Glucose 1 h (mg/dL)		p-value
		< 155 mg/dL	≥ 55 mg/dL	p-value
Triglycerides [mg/dL, median (IQR)]	293	99.0 (64)	125.0 (92)	0.011
HDL-cholesterol (37)	292	51.1 (12.1)	50.6 (11.9)	0.779
LDL-cholesterol (37)	289	117.1 (31.5)	121.0 (3.9)	0.373
Total-cholesterol (37)	294	190.9 (37.1)	198.6 (39.7)	0.138
hsCRP [mg/dL, median (IQR)]	223	8.3 (10.2)	7.6 (9.8)	0.464
Creatinine [mg/dL, median (IQR)]	289	0.6 (0.2)	0.6 (0.2)	0.488
HOMA-IR [median (IQR)]	295	3.1 (2.3)	3.5 (3.4)	0.103
HOMA-β [median (IQR)]	295	263.6 (217.1)	233.1 (220.7)	0.549
Insulinogenic index [median (IQR)]	288	1.78 (1.75)	1.10 (1.29)	< 0.001

HDL high-density lipoprotein cholesterol, HOMA-β homeostatic model assessment for cell-β function, HOMA-IR homeostatic model assessment for insulin resistance, hsCRP high sensitivity C-reactive protein, LDL low-density lipoprotein, IQR Interquartile range, SD standard deviation

ISSN: 1758-5996