The relationship between central obesity and bone mineral density: a Mendelian randomization study

Table 1 Sample characteristics for traits in current study

Traits	Sample size	Independent SNPs number	Approximate variance Explained (%)
BMD	265,627	–^*	–^*
WC	224,459	45	1.1
WCadjBMI	245,746	63	1.3
HC	213,038	52	1.4
HCadjBMI	211,114	72	2.1
WHR	21,244	28	0.7
WHRadjBMI	224,452	36	0.1

^*The independent SNPs number and variance explained by SNPs were different between each MR analysis

ISSN: 1758-5996