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Table 5 Combining tertiles of baseline and change in HbA1c for incident hypertension

From: Associations of the baseline level and change in glycosylated hemoglobin A1c with incident hypertension in non-diabetic individuals: a 3-year cohort study

Baseline HbA1c (%)

Change in HbA1c

N

n (%)

Unadjusted OR (95% CI)

Adjusted OR (95% CI)

Model 1

Model 2

Model 3

Tertile1 (4.0–5.6) (N = 892)

Tertile1 (≤ − 0.4)

168

15 (8.9)

1 (ref)

1 (ref)

1 (ref)

1 (ref)

 

Tertile2 (− 0.3–0.2)

260

33 (12.7)

1.483 (0.779–2.823)

1.550 (0.810–2.967)

1.721 (0.867–3.415)

1.757 (0.883–3.497)

 

Tertile3 (≥ − 0.1)

464

59 (12.7)

1.486 (0.818–2.698)

1.484 (0.813–2.708)

1.505 (0.797–2.843)

1.444 (0.762–2.738)

Tertile2 (5.7–5.9) (N = 904)

Tertile1 (≤ − 0.4)

357

45 (12.6)

1.471 (0.795–2.723)

1.317 (0.708–2.452)

1.216 (0.629–2.351)

1.221 (0.630–2.365)

 

Tertile2 (− 0.3–0.2)

289

48 (16.6)

2.032 (0.897–1.630)

1.777 (0.955–3.308)

1.953 (1.008–3.784)

1.944 (1.001–3.775)

 

Tertile3 (≥ − 0.1)

258

45 (17.4)

2.155 (1.159–4.007)

1.950 (1.042–3.649)

2.196 (1.126–4.284)

2.057 (1.051–4.028)

Tertile3 (6.0–6.4) (N = 795)

Tertile1 (≤ − 0.4)

441

59 (13.4)

1.575 (0.867–2.862)

1.274 (0.695–2.334)

1.226 (0.645–2.333)

1.190 (0.623–2.272)

 

Tertile2 (− 0.3–0.2)

201

36 (17.9)

2.225 (1.172–4.226)

1.784 (0.931–3.417)

1.626 (0.812–3.256)

1.564 (0.778–3.144)

 

Tertile3 (≥ − 0.1)

153

44 (28.8)

4.117 (2.181–7.773)

3.442 (1.808–6.551)

3.063 (1.519–6.175)

2.729 (1.346–5.533)

p value

   

 < 0.001

0.001

0.004

0.015

  1. Model 1: adjusted for age (continuous), sex, education level, current smoking, current alcohol consumption; Model 2: Model 1 + body mass index, fasting plasma glucose, total cholesterol, triglycerides, high-density lipoprotein cholesterol, and systolic blood pressure at baseline (all continuous); Model 3: Model 2 + change in body mass index (continuous); CI confidence interval, HbA1c glycated hemoglobin A1c