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Fig. 2 | Diabetology & Metabolic Syndrome

Fig. 2

From: Epigallocatechin-3-gallate ameliorates hepatic damages by relieve FGF21 resistance and promotion of FGF21–AMPK pathway in mice fed a high fat diet

Fig. 2

Effects of EGCG on the expression of lipogenesis-related genes and FGF21/AMPK protein in liver tissue. A The levels of FGFR 2 and FGFR3. B Serum FGF21 levels. C TG levels in liver tissue. D Expression of PPAR–FGF21–AMPK by Western blotting. E Protein densities were measured by Western blotting, F Expression levels of lipogenesis-related genes mRNA were determined in liver tissue. G Immunohistochemical assay FGF21 of liver; #p < 0.05, ##p < 0.01, ###p < 0.001, ####p < 0.0001 vs CON; *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001 vs HFD. (the CON, n = 10), HFD (n = 12) and HFD + EGCG (n = 12)

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