Table 1 Comparison of clinical characteristics between patients with and without carotid atherosclerotic plaque
Characteristic | Without carotid plaque | With carotid plaque | p-value |
|---|---|---|---|
(n = 223) | (n = 280) | ||
Demographic characteristics | |||
Age (years) | 51.6 ± 9.8 | 61.5 ± 10.1 | < 0.001 |
Male | 133 (59.6) | 164 (58.6) | 0.880 |
WC (cm) | 88.6 ± 9.2 | 89.9 ± 10.8 | 0.033 |
BMI (kg/m2) | 23.9 ± 3.1 | 24.8 ± 3.6 | 0.004 |
Medical history and Clinical condition | |||
Smoking history | 70 (31.4) | 103 (36.8) | 0.242 |
Hypertension | 75 (33.6) | 131 (46.8) | 0.004 |
SBP (mmHg) | 134.4 ± 18.5 | 139.3 ± 19.3 | 0.004 |
DBP (mmHg) | 83.9 ± 12.2 | 80.9 ± 12.2 | 0.006 |
Duration of diabetes (years) | 4 (0, 10) | 8 (3, 11) | < 0.001 |
DR | 23 (13.9) | 59 (27.7) | 0.005 |
DPN | 72 (55.0) | 103 (57.2) | 0.752 |
DN | 15 (9.3) | 51 (24.4) | < 0.001 |
Stroke | 5 (2.2) | 17 (6.1) | 0.062 |
NAFLD | 116 (58.0) | 117 (50.2) | 0.128 |
Laboratory examination | |||
Adropin (ng/ml) | 20.5 ± 4.0 | 20.6 ± 3.7 | 0.763 |
FBG (mmol/L) | 9.2 ± 3.4 | 9.1 ± 3.5 | 0.852 |
2hPBG (mmol/L) | 13.1 ± 4.8 | 13.2 ± 5.1 | 0.751 |
HbA1c (%) | 10.1 ± 2.5 | 10.7 ± 2.7 | 0.056 |
HOMA-IR | 13.8 (7.6, 27.7) | 17.9 (8.7, 32.3) | 0.023 |
TG (mmol/L) | 2.2 ± 1.8 | 1.9 ± 1.5 | 0.057 |
TC (mmol/L) | 5.0 ± 1.2 | 4.9 ± 1.2 | 0.192 |
HDL-C (mmol/L) | 1.2 ± 0.4 | 1.3 ± 0.5 | 0.167 |
LDL-C (mmol/L) | 3.2 ± 1.0 | 3.1 ± 1.1 | 0.305 |
eGFR (ml/min/1.73 m2) | 124.0 ± 38.1 | 106.8 ± 36.0 | < 0.001 |
UA (μmol/L) | 344.8 ± 92.4 | 345.0 ± 91.3 | 0.981 |
hs-CRP (mg/L) | 1.2 (0.6, 2.3) | 1.4 (0.7, 2.9) | 0.090 |
HCY (μmol/L) | 10.6 ± 3.3 | 11.4 ± 3.8 | 0.018 |
Administered drugs | |||
Insulin | 36 (16.1) | 58 (20.7) | 0.234 |
OADs | 123 (55.4) | 173 (62.5) | 0.133 |
Statins | 6 (2.7) | 17 (6.1) | 0.112 |