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Table 3 ORs (95% CIs) of DPN according to quartiles of the plasma 1,5-AG in patients under mild-to-moderate hyperglycemia

From: Plasma 1,5-anhydro-d-glucitol is associated with peripheral nerve function and diabetic peripheral neuropathy in patients with type 2 diabetes and mild-to-moderate hyperglycemia

 

Q1

Q2

Q3

Q4

p value for trend

n

142

143

146

143

–

DPN, n (%)

52 (36.6)

35 (24.5)

31 (21.2)

19 (13.3)

–

Model 0

3.77 (2.09–6.81)

2.12 (1.14–3.91)

1.76 (0.94–3.29)

1—reference

< 0.001

Model 1

3.74 (1.90–7.38)

2.31 (1.19–4.45)

1.54 (0.79–2.99)

1—reference

0.001

Model 2

2.40 (1.07–5.41)

1.71 (0.82–3.56)

1.30 (0.62–2.71)

1—reference

0.022

Model 3

2.72 (1.16–6.34)

1.85 (0.87–3.97)

1.29 (0.59–2.81)

1—reference

0.011

  1. Model 0: crude
  2. Model 1: adjusted for age, sex, diabetic duration, BMI, SBP, DBP, hypertension and smoking
  3. Model 2: additionally adjusted for lipid profiles, UA, HOMA-IR, HbA1c, eGFR and UACR
  4. Model 3: additionally adjusted for statins treatment and glucose-lowering therapies