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Fig. 2 | Diabetology & Metabolic Syndrome

Fig. 2

From: Circular RNA circZNF532 facilitates angiogenesis and inflammation in diabetic retinopathy via regulating miR-1243/CARM1 axis

Fig. 2

Depletion of circZNF532 alleviated proliferation, migration, invasion, tube formation and pro-inflammatory cytokine release induced by HG in hRMECs. After si-circZNF532 or si-NC transfection, hRMECs were treated with NG or HG for 48 h. A The expression of circZNF532 was examined by qRT-PCR. B Cell proliferation was tested by colony formation assay. C and D Cell migration and invasion were assessed by transwell assay. E Tube formation assay was utilized to evaluate angiogenesis. F–H The levels of pro-inflammatory cytokines (IL-1β, IL-6 and TNF-α) were measured using ELISA assay. *P < 0.05

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Diabetology & Metabolic Syndrome

ISSN: 1758-5996

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