Table 1 Baseline clinical characteristics, conventional two-dimensional echocardiographic parameters between T2DM patients and normal subjects
Variable | Normal (50) | T2DM (48) | p-value |
|---|---|---|---|
Clinical | |||
Age (yrs) | 50.38 ± 15.27 | 53.79 ± 11.24 | 0.212 |
Male (%) | 25(50) | 25(52) | 0.846 |
BMI (kg/m2) | 22.92 ± 1.17 | 22.68 ± 1.44 | 0.358 |
Heart Rate (bpm) | 73.72 ± 10.74 | 76.25 ± 9.50 | 0.221 |
SBP (mmHg) | 121.94 ± 11.60 | 127.15 ± 12.91 | 0.038 |
DBP (mmHg) | 76.78 ± 8.33 | 77.79 ± 8.99 | 0.565 |
Fasting plasma glucose (mmol/L) | 4.82 ± 0.63 | 13.28 ± 4.36 | < 0.001 |
HbA1c (%) | 5.02 ± 0.62 | 10.13 ± 2.15 | < 0.001 |
TCH (mmol/L) | 3.91 ± 0.64 | 3.99 ± 0.77 | 0.585 |
TG (mmol/L) | 1.10 ± 0.30 | 1.19 ± 0.60 | 0.365 |
HDL (mmol/L) | 1.27 ± 0.29 | 1.19 ± 0.36 | 0.272 |
LDL (mmol/L) | 2.06 ± 0.50 | 2.27 ± 0.62 | 0.060 |
Medical treatment in hospitalization (%) | |||
Diet treatment | 0 (0) | 0 (0) | |
Oral drug | 0 (0) | 12 (25) | |
Insulin | 0 (0) | 26 (54) | |
Insulin + Oral drug | 0 (0) | 10 (21) | |
Echocardiography | |||
LAd (mm) | 33.50 ± 3.09 | 35.46 ± 3.91 | 0.007 |
IVSd (mm) | 8.85 ± 0.87 | 9.35 ± 1.23 | 0.021 |
LVPWd (mm) | 8.54 ± 0.95 | 9.04 ± 1.15 | 0.021 |
LVDd (mm) | 46.30 ± 2.52 | 46.96 ± 3.68 | 0.302 |
LVEDV (ml) | 74.54 ± 13.47 | 72.52 ± 14.07 | 0.470 |
LVESV (ml) | 25.80 ± 6.32 | 27.44 ± 5.61 | 0.179 |
LVEF (%) | 65.59 ± 4.01 | 62.06 ± 4.87 | < 0.001 |
E (m/s) | 0.88 ± 0.13 | 0.79 ± 0.13 | < 0.001 |
A (m/s) | 0.68 ± 0.14 | 0.69 ± 0.19 | 0.924 |
E/A | 1.34 ± 0.30 | 1.22 ± 0.34 | 0.079 |
e′ (m/s) | 0.13 ± 0.03 | 0.09 ± 0.02 | < 0.001 |
a′ (m/s) | 0.09 ± 0.02 | 0.10 ± 0.02 | < 0.001 |
E/e′ | 7.26 ± 1.60 | 10.35 ± 2.55 | < 0.001 |