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Table 4 The results of association analysis between alleles and T2DM

From: Association analysis of SOCS3, JAK2 and STAT3 gene polymorphisms and genetic susceptibility to type 2 diabetes mellitus in Chinese population

Gene

SNPs

Allele

NC

T2DM

P

OR (95% CI)

Observed

Adjust

SOCS3

rs4969168

A/G

462/598

435/671

0.043

0.045

0.84 (0.71–1.00)

rs2280148

G/T

334/1000

198/916

 < 0.001

 < 0.001

0.65 (0.53–0.79)

JAK2

rs10974914

A/G

407/865

415/695

0.007

0.006

1.27 (1.07–1.50)

rs10815157

C/G

366/578

346/762

0.001

 < 0.001

0.72 (0.60–0.86)

STAT3

rs1053005

A/G

416/646

460/656

0.311

0.330

1.09 (0.92–1.29)

  1. OR, odds ratio