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Fig. 5 | Diabetology & Metabolic Syndrome

Fig. 5

From: Dietary supplementation of inulin alleviates metabolism disorders in gestational diabetes mellitus mice via RENT/AKT/IRS/GLUT4 pathway

Fig. 5

Changes of the candidate genes expressions between GDM and Inulin-H groups by using RT2 profiler PCR array. A Scatter plot of the results of every gene expression. The central diagonal line indicates unchanged gene expression, while the outer diagonal lines indicate the selected fold regulation threshold. Yellow dots denote genes with upregulated expression, while blue dots represent genes with downregulated expression. Black dots denote genes with unchanged expression. B Cluster gram of genes with significantly upregulated or downregulated expression. Each column expresses a group, and each row represents a gene. Various colors display the magnitude of gene expression and the degree of gene expression from minimum to maximum is exhibited from green to red. C Heat map of the results of every gene expression. Different colors show the different levels of gene expression. Colors ranging from blue to red means downregulated to upregulated gene expression. The most differentially-expressed gene (RETN) validated with qPCR in hepatic (D) and adipose tissues (E). Correlation between RETN expression in hepatic (F) and adipose tissues (G) and fasting glucose levels. Differences were assessed by t-test or Wilcoxon rank-sum test, as appropriate. Correlation analysis was performed with Pearson pairwise test. **< 0.01 vs. NCD group; ##P < 0.01 vs. GDM

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