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Fig. 4 | Diabetology & Metabolic Syndrome

Fig. 4

From: Leucine imparts cardioprotective effects by enhancing mTOR activity and mitochondrial fusion in a myocardial ischemia/reperfusion injury murine model

Fig. 4

Reactive oxygen species (ROS) production in myocardium pretreated with leucine (Leu). ROS generation was examined after inducing ischemia/reperfusion injury in wild-type, mTOR+/−, and HFD-induced obese mice. Leu treatment resulted in decreased ROS generation in wild-type and HFD-induced obese mice, and this effect was inhibited by Rap. *p < 0.05, vs. control (Cont). mTOR, mammalian target of rapamycin; Rap, rapamycin; RFU, relative fluorescence units

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