Table 1 Clinical and biochemical characteristics of study participants according to serum albumin quartiles
Characteristics | Q1 | Q2 | Q3 | Q4 | P |
|---|---|---|---|---|---|
21.70–37.60 | 37.70–41.30 | 41.40–44.40 | 44.50–57.60 | ||
(n = 368) | (n = 364) | (n = 367) | (n = 366) | ||
Albumin (g/L) | 35.50 (33.10–36.80) | 39.70 (38.80–40.50) | 42.70 (42.00–43.50) | 46.60 (45.40–48.03) | 0.000 |
Male/Female | 185/183 | 177/187 | 179/188 | 183/183 | 0.958 |
Age (years) | 62.75 ± 11.13 | 60.63 ± 11.25 | 58.89 ± 11.23 | 57.36 ± 11.02 | 0.000 |
BMI (kg/m2) | 23.05 ± 3.40 | 24.57 ± 4.21 | 24.59 ± 3.60 | 24.73 ± 3.48 | 0.000 |
Diabetic duration (years) | 8.00 (3.00–12.00) | 8.00 (3.00–11.00) | 6.00 (2.00–10.00) | 6.00 (2.00–10.00) | 0.002 |
SBP (mmHg) | 131.50 (118.00–149.00) | 130.00 (116.25–144.75) | 130.00 (119.00–145.00) | 129.00 (119.00–140.25) | 0.434 |
DBP (mmHg) | 70.58 ± 11.73 | 71.54 ± 12.46 | 71.99 ± 11.81 | 73.84 ± 12.40 | 0.004 |
FBG (mmol/L) | 10.32 (7.41–14.59) | 9.14 (6.80–13.16) | 9.65 (6.90–13.17) | 8.94 (7.09–12.19) | 0.022 |
HbA1c (%) | 10.20 (8.10–12.20) | 9.30 (7.80–11.10) | 8.90 (7.30–10.80) | 8.30 (7.10–10.10) | 0.000 |
TC (mmol/L) | 4.26 (3.50–5.23) | 4.54 (3.83–5.35) | 4.86 (4.16–5.63) | 4.98 (4.30–5.72) | 0.000 |
TG (mmol/L) | 1.32 (0.94–1.98) | 1.66 (1.18–2.46) | 1.81 (1.21–2.77) | 1.93 (1.30–3.09) | 0.000 |
HDL-C(mmol/L) | 1.09 (0.89–1.31) | 1.08 (0.91–1.27) | 1.16 (0.96–1.36) | 1.20 (1.00–1.42) | 0.000 |
LDL-C(mmol/L) | 2.45 (1.87–3.23) | 2.56 (2.09–3.24) | 2.76 (2.18–3.34) | 2.87 (2.19–3.47) | 0.000 |
ALT (U/L) | 14.10 (10.13–22.00) | 16.60 (12.00–23.80) | 19.90 (14.00–29.00) | 20.90 (15.68–32.00) | 0.000 |
AST (U/L) | 16.35 (12.70–21.38) | 17.05 (14.00–21.33) | 19.20 (15.40–24.90) | 21.10 (17.28–27.30) | 0.000 |
GGT (U/L) | 20.15 (13.60–36.80) | 23.05 (15.53–39.50) | 26.80 (16.80–42.40) | 28.45 (19.30–48.03) | 0.000 |
UA (μmol/L) | 290.70 (221.05–358.33) | 297.70 (243.12–369.12) | 308.15 (247.18–373.58) | 319.60 (267.90–393.70) | 0.000 |
CysC (mg/L) | 1.01 (0.76–1.43) | 0.88 (0.71–1.16) | 0.86 (0.71–1.05) | 0.82 (0.71–0.99) | 0.000 |
Serum Cr (μmol/L) | 68.20 (53.93–97.95) | 61.90 (51.10–81.28) | 63.10 (50.80–76.20) | 61.35 (50.68–73.73) | 0.000 |
eGFR (mL/min/1.73 m2) | 88.78 (60.95–103.96) | 97.62 (77.30–107.54) | 97.43 (82.73–109.14) | 100.14 (88.51–110.31) | 0.000 |
ACR (mg/g) | 60.50 (19.60–481.70) | 25.43 (13.15–68.14) | 23.10 (11.21–56.24) | 19.17 (8.78–42.78) | 0.000 |
NLR | 3.36 (2.11–4.71) | 2.58 (1.90–3.66) | 2.43 (1.79–3.48) | 2.41 (1.74–3.31) | 0.000 |
RDW | 13.05 (12.50–13.70) | 12.90 (12.40–13.60) | 12.90 (12.50–13.60) | 13.00 (12.50–13.63) | 0.501 |
ABI | 1.04 (0.97–1.11) | 1.04 (1.00–1.09) | 1.05 (1.00–1.11) | 1.05 (1.00–1.10) | 0.033 |
VPT (V) | 16.00 (12.00–28.00) | 14.00 (10.00–20.00) | 12.00 (10.00–18.00) | 12.00 (8.00–16.00) | 0.000 |
DPN (n, %) | 115 (31.25) | 61 (16.76) | 36 (9.81) | 19 (5.19) | 0.000 |