Performance of waist-to-height ratio as a screening tool for identifying cardiometabolic risk in children: a meta-analysis

Table 2 Summarised performance of WHtR screening for CMRs in children and adolescents

Outcome	Population	Prevalence	Threshold effect (correlation coefficient)	P-value	AUSROC (95% CI)	Sensitivity (95% CI)	Specificity (95% CI)	DOR (95% CI)
CMR₃ [16, 20, 22,23,24, 26, 38, 42, 44, 53, 68,69,70,71,72,73,74,75,76,77,78, 83, 84]	99,331	0.07	− 0.053	0.811	0.91 (0.88, 0.93)	0.84 (0.76, 0.90)	0.84 (0.78, 0.88)	28 (14, 54)
CMR₂ [20, 21, 26, 43, 46, 53, 65,66,67]	46,448	0.11	0.271	0.481	0.85 (0.81, 0.88)	0.83 (0.64, 0.93)	0.77 (0.66, 0.84)	16 (6, 45)
CMR₁ [20, 26, 43, 53]	20,268	0.52	− 0.212	0.788	0.75 (0.71, 0.79)	0.55 (0.43, 0.66)	0.84 (0.74, 0.91)	7 (3, 15)
Elevated FBG [20, 42,43,44,45,46,47, 79]	13,749	0.21	0.949	< 0.001	0.59 (0.55, 0.63)	0.54 (0.36, 0.70)	0.62 (0.37, 0.82)	2 (1, 3)
Elevated BP [20, 23, 42, 43, 46,47,48,49,50,51,52,53,54,55,56,57, 80,81,82,83,84,85]	101,786	0.15	0.801	< 0.001	0.69 (0.65,0.73)	0.55 (0.45,0.64)	0.74 (0.65,0.81)	3 (3,4)
Dyslipidaemia [20, 23, 42,43,44, 46, 59, 83, 84]	73,092	0.14	0.859	< 0.001	0.66 (0.62,0.70)	0.54 (0.41,0.66)	0.69 (0.60,0.77)	3 (2,3)
Elevated TG [20, 23, 42,43,44, 46]	12,599	0.08	0.860	0.026	0.70 (0.66, 0.74)	0.58 (0.31, 0.80)	0.71 (0.50, 0.86)	3 (2, 5)
Low HDL-C [20, 23, 42,43,44, 46]	12,604	0.10	0.930	0.008	0.70 (0.66, 0.74)	0.50 (0.24, 0.77)	0.74 (0.58, 0.86)	3 (2, 5)
Central obesity [16, 20, 61,62,63,64, 86]	148,115	0.18	− 0.308	0.502	0.96 (0.94, 0.97)	0.91 (0.84, 0.95)	0.90 (0.86, 0.93)	88 (40, 195)

WHtR waist-to-height ratio, CMR cardiometabolic risk factor, CMR₃ presenting with at least three CMRs, CMR₂ presenting with at least two CMRs; CMR₁ presenting with least one of CMRs, FBG fasting blood glucose, BP blood pressure, TG triglyceride, HDL-C High-density leptin cholesterol, AUSROC area under the summary receiver operating characteristic, DOR diagnostic odds ratio, CI confidence interval
The results of pooled elevated total cholesterol, high low-density leptin cholesterol, and SBP/DBP blood pressure were not reported due to models unstable caused by limited original studies

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