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Table 2 Summarised performance of WHtR screening for CMRs in children and adolescents

From: Performance of waist-to-height ratio as a screening tool for identifying cardiometabolic risk in children: a meta-analysis

Outcome Population Prevalence Threshold effect (correlation coefficient) P-value AUSROC (95% CI) Sensitivity (95% CI) Specificity (95% CI) DOR (95% CI)
CMR3 [16, 20, 22,23,24, 26, 38, 42, 44, 53, 68,69,70,71,72,73,74,75,76,77,78, 83, 84] 99,331 0.07 − 0.053 0.811 0.91 (0.88, 0.93) 0.84 (0.76, 0.90) 0.84 (0.78, 0.88) 28 (14, 54)
CMR2 [20, 21, 26, 43, 46, 53, 65,66,67] 46,448 0.11 0.271 0.481 0.85 (0.81, 0.88) 0.83 (0.64, 0.93) 0.77 (0.66, 0.84) 16 (6, 45)
CMR1 [20, 26, 43, 53] 20,268 0.52 − 0.212 0.788 0.75 (0.71, 0.79) 0.55 (0.43, 0.66) 0.84 (0.74, 0.91) 7 (3, 15)
Elevated FBG [20, 42,43,44,45,46,47, 79] 13,749 0.21 0.949  < 0.001 0.59 (0.55, 0.63) 0.54 (0.36, 0.70) 0.62 (0.37, 0.82) 2 (1, 3)
Elevated BP [20, 23, 42, 43, 46,47,48,49,50,51,52,53,54,55,56,57, 80,81,82,83,84,85] 101,786 0.15 0.801  < 0.001 0.69 (0.65,0.73) 0.55 (0.45,0.64) 0.74 (0.65,0.81) 3 (3,4)
Dyslipidaemia [20, 23, 42,43,44, 46, 59, 83, 84] 73,092 0.14 0.859  < 0.001 0.66 (0.62,0.70) 0.54 (0.41,0.66) 0.69 (0.60,0.77) 3 (2,3)
Elevated TG [20, 23, 42,43,44, 46] 12,599 0.08 0.860 0.026 0.70 (0.66, 0.74) 0.58 (0.31, 0.80) 0.71 (0.50, 0.86) 3 (2, 5)
Low HDL-C [20, 23, 42,43,44, 46] 12,604 0.10 0.930 0.008 0.70 (0.66, 0.74) 0.50 (0.24, 0.77) 0.74 (0.58, 0.86) 3 (2, 5)
Central obesity [16, 20, 61,62,63,64, 86] 148,115 0.18 − 0.308 0.502 0.96 (0.94, 0.97) 0.91 (0.84, 0.95) 0.90 (0.86, 0.93) 88 (40, 195)
  1. WHtR waist-to-height ratio, CMR cardiometabolic risk factor, CMR3 presenting with at least three CMRs, CMR2 presenting with at least two CMRs; CMR1 presenting with least one of CMRs, FBG fasting blood glucose, BP blood pressure, TG triglyceride, HDL-C High-density leptin cholesterol, AUSROC area under the summary receiver operating characteristic, DOR diagnostic odds ratio, CI confidence interval
  2. The results of pooled elevated total cholesterol, high low-density leptin cholesterol, and SBP/DBP blood pressure were not reported due to models unstable caused by limited original studies