|
Total
|
rs780094
|
rs780093
|
rs1260326
|
---|
CC (n = 2543)
|
CT (n = 4169)
|
TT (n = 1879)
|
CC (n = 2509)
|
CT (n = 4180)
|
TT (n = 1902)
|
CC (n = 2478)
|
CT (n = 4174)
|
TT (n = 1939)
|
---|
With MetS
|
50.9%
|
28.1%
|
49%
|
23%*
|
28.2%
|
48%
|
23.8%*
|
27.4%
|
49.0%
|
23.6%*
|
Without MetS
|
49.1%
|
32.5%
|
47.1%
|
20.4%*
|
31.6%
|
48.2%
|
20.2%*
|
31.4%
|
47.7%
|
20.9%*
|
Male
|
42.6%
|
30.9%
|
47.8%
|
21.2%
|
30.8%
|
47.5%
|
21.6%
|
30.3%
|
48.0%
|
21.8%
|
Female
|
57.4%
|
29.7%
|
48.0%
|
22.2%
|
29.3%
|
48.4%
|
22.3%
|
28.8%
|
48.5%
|
22.7%
|
Smoking never
|
83%
|
30.6%
|
47.9%
|
21.5%
|
30.3%
|
48.0%
|
21.7%
|
29.7%
|
48.4%
|
21.9%
|
Ex-smoker and smoker
|
17%
|
28.0%
|
48.9%
|
23.1%
|
28.0%
|
49.0%
|
23.0%
|
27.8%
|
48.2%
|
23.9%
|
Age (years)
|
39 ± 16
|
39 ± 17
|
39 ± 16
|
40 ± 17
|
39 ± 17
|
39 ± 16
|
40 ± 17
|
39 ± 17
|
39 ± 16
|
39.5 ± 16.6
|
WC (cm)
|
85 ± 21 (53.3%)a
|
85 ± 21
|
85 ± 21
|
85 ± 22
|
85 ± 22
|
85 ± 21
|
85 ± 22
|
85 ± 22
|
85 ± 21
|
85.4 ± 21.5
|
HDL-C (mg/dl)
|
42 ± 14 (69.8%)b
|
43 ± 14
|
42 ± 14
|
42 ± 15
|
43 ± 14
|
42 ± 14
|
42 ± 14
|
43 ± 14
|
42 ± 14
|
42 ± 14
|
TG (mg/dl)
|
137 ± 86 (41.8%)c
|
125 ± 75
|
139 ± 88
|
150 ± 91†
|
126 ± 81
|
137 ± 84
|
152 ± 92†
|
125 ± 74
|
138 ± 88
|
151 ± 92†
|
FBS (mg/dl)
|
89 ± 25 (22.3%)d
|
90 ± 26
|
89 ± 23
|
88 ± 27
|
90 ± 27
|
89 ± 23
|
89 ± 27
|
90 ± 27
|
89.4 ± 23.1
|
88.8 ± 26.5
|
SBP (mmHg)
|
110 ± 26(28.8%)e
|
110 ± 26
|
110 ± 25
|
111 ± 27
|
110 ± 26
|
110 ± 25
|
111 ± 26
|
110 ± 26
|
110 ± 26
|
111.1 ± 26
|
DBP (mmHg)
|
73 ± 17 (28.8%)e
|
72 ± 17
|
73 ± 17
|
73 ± 18
|
72 ± 18
|
73 ± 17
|
73 ± 18
|
72 ± 18
|
72 ± 17
|
73 ± 17
|
- From the 6th row onwards, data are presented as mean ± SD
- aFrequency of subjects with high waist circumference: waist circumference ≥ 90 cm for both genders
- bFrequency of subjects low HDL-C: HDL-C < 40 mg/dl in men and < 50 mg/dl in women and drug treatment
- cFrequency of subjects high TG: TG ≥ 150 mg/dl and drug treatment
- dFrequency of subjects high FBS: FBS ≥ 100 mg/dl and drug treatment
- eFrequency of subjects high blood pressure: SBP ≥ 130 mmHg and DBP ≥ 85 mmHg and drug treatment
- *Frequency differences of genotypes between MetS and without MetS, P < 0.05
- †TT vs. CC, P < 0.05 and TT vs CT, P < 0.05