Table 2 Characteristics of Brazilian women with PCOS in the studies included in the systematic review

BMI-unmatched studies

Avila et al. 2014 [30]

30.6 ± 9.3/–

NA

NA

NA

NA

NA

Azevedo et al. 2011 [23]

29.3 ± 6.7/24.1 ± 4.4*

91.2 ± 15.7/77.1 ± 9.6*

SBP: 114.8 ± 13.3/111.5 ± 10.7*

DBP: 72.6 ± 10.7/72.1 ± 10.3

TC (mmol/L):

4.82 ± 1.09/4.57 ± 1.19

HDL (mmol/L):

1.05 ± 0.29/1.39 ± 0.49*

LDL (mmol/L):

NA

TGL (mmol/L):

1.56 ± 0.91/1.13 ± 0.6 *

4.64 ± 0.67/4.25 ± 0.62*

NA

Carvalho et al. 2017 [31]

30.1 ± 5.4/ 23.2 ± 4.23*

98.0 (17.0)/71.5 (16.0)*

NA

NA

4.83 ± 0.4/ 4.7 ± 0.58

3.54(4.8)/1.68(1.6)*

Cerqueira et al. 2010 [24]

27.7 ± 5.4/ 24 ± 4.2*

84.5 ± 11.3/ 78.9 ± 10.0*

SBP: 117.5 ± 11.9/104.0 ± 10.3*

DBP: 77.7 ± 9.8/68.7 ± 8.1*

TC (mmol/L):

4.57 ± 0.81/4.11 ± 0.76*

HDL (mmol/L):

1.16 ± 0.24/ 1.41 ± 0.43*

LDL (mmol/L):

2.29 ± 0.92/2.14 ± 0.75

TGL (mmol/L):

1.3 ± 0.78/0.94 ± 0.43*

4.88 ± 0.68/4.68 ± 0.41*

3.6 ± 3.7/1.9 ± 0.9*

Costa et al. 2012 [29]

29.6 ± 6.6/–

NA

SBP:115.5 ± 13.0/–

DBP:73.3 ± 10.3/–

TC (mmol/L):

4.88 ± 1.08/–

HDL (mmol/L):

01.14 ± 0.28/–

LDL (mmol/L):

3.11 ± 1.07/–

TGL (mmol/L): 1.54 ± 0.81/–

4.62 ± 0.68/–

NA

de Medeiros et al. 2014 [48]

29.9 ± 7.0/–

88.0 ± 16.3/–

NA

NA

5.11 ± 0.78/–

1.93 ± 1.21/–

Gabrielli et al. 2012 [26]

24.2 (17.7–30.7)/ 24.1 (18.1–30.1)

74 (56–92)/75 (60–90)

SBP: 119 (99–139)/122 (102–142)

DBP: 74 (60–88)/ 74 (59.5–89.5)

NA

NA

NA

Graff et al. 2017 [44]

29.4 ± 6.4/27.2 ± 5.8*

86.6 ± 14.1/83.6 ± 12.3

SBP:118.2 ± 13.0/112.4 ± 11.1*

DBP:77.4 ± 9.9/72.8 ± 10.0*

TC (mmol/L):

4.49 ± 0.89/4.5 ± 0.79

HDL (mmol/L):

1.18 ± 0.31/1.31 ± 0.28*

LDL (mmol/L):

2.75 ± 0.71/2.72 ± 0.63

TGL (mmol/L):

0.99(0.69–1.53) /0.87(0.6–1.16)

4.85 ± 0.47/4.82 ± 0.44

3.4(1.8–4.7)/2.1(1.5–2.8)*

Kogure et al. 2012 [32]

28.7 ± 4.4/27.1 ± 5.1

NA

NA

TC (mmol/L):

5.42 ± 1.24/5.47 ± 1.19

HDL (mmol/L):

1.38 ± 0.31/1.52 ± 0.28

LDL (mmol/L): 3.29 ± 0.92/3.4 ± 0.96

TGL (mmol/L): 1.65 ± 0.93/1.19 ± 0.75*

5.82 ± 0.99/5.73 ± 1.09

2.3 ± 2.3/1.6 ± 0.8*

Maciel et al. 2014 [34]

29.6 ± 6.9/–

90.1 ± 15.2/–

NA

TC (mmol/L): 4.42 ± 0.82/–

HDL (mmol/L): 1.3 ± 0.36/–

LDL (mmol/L): 2.55 ± 0.67/–

TGL (mmol/L): 1.3 ± 0.7/–

4.95 ± 0.57/–

3.8 ± 3.3/–

Melo et al. 2011^a [35]

31.3 ± 8.7/24.4 ± 4.9*

98.6 ± 17.7/84.8 ± 12.4

SBP:

121.5 ± 15.2/111.5 ± 10.8*

DBP:

7 8 ± 10.4/71.7 ± 8.2*

TC (mmol/L): 4.76 ± 1.04/4.93 ± 0.84

HDL (mmol/L): 1.16 ± 0.27/1.41 ± 0.28*

LDL (mmol/L): 2.9 ± 0.92/2.82 ± 0.72

TGL (mmol/L): 1.49 ± 0.82/0.95 ± 0.44*

5.17 ± 1.41/4.58 ± 0.49*

4.5 ± 4.9/ 1.5 ± 1.1*

Oliveira et al. 2013^b [36]

30.2 ± 6.5/27.1 ± 6.2

NA

SBP:

111.8 ± 12.0 / 107.3 ± 15.0

DBP:

70.2 ± 9.0/71 ± 13.5

TC (mmol/L): NA

HDL (mmol/L): 1.3 ± 0.38/1.49 ± 0.35

LDL (mmol/L): NA

TGL (mmol/L): 1.32 ± 0.91/1.31 ± 0.74

4.82 ± 0.97/4.54 ± 0.47

4.4 ± 6.8 / 2.1 ± 1.1

Pedroso et al. 2012 [37]

31.9 ± 8.2/–

99 ± 16.6)

SBP:

122.5 ± 18.7/–

DBP:

79 ± 11/–

TC (mmol/L): 4.86 ± 1.01/–

HDL (mmol/L): 1.22 ± 0.32/–

LDL (mmol/L): 2.94 ± 0.87/–

TGL (mmol/L): 1.48 ± 0.84/–

5.04 ± 1.08/–

NA

Pontes et al. 2012 [38]

31.8 ± 7.6/–

92.2 ± 16.0

SBP: 116.3 ± 14.4/–

DBP: 75.1 ± 10.4/–

TC (mmol/L): 4.73 ± 0.9/–

HDL (mmol/L): 1.21 ± 0.33/–

LDL (mmol/L):

2.90 ± 0.77/–

TGL (mmol/L):

1.43 ± 0.91/–

4.87 ± 0.38/–

NA

Radavelli-Bagatini et al. 2013 [45]

31.0 ± 7.9/23.4 ± 4.6*

92.2 ± 18.8/74.5 ± 10.2*

SBP: 124.6 ± 19.9/111.5 ± 13.0*

DBP: 79.2 ± 12.5/71.8 ± 10.6*

TC (mmol/L):

4.81 ± 1.16/4.24 ± 0.9*

HDL (mmol/L): 1.32 ± 0.28/1.52 ± 0.36*

LDL (mmol/L): 2.95 ± 0.98/2.09 ± 0.72*

TGL (mmol/L): NA

NA

NA

Ramos et al. 2015 [46]

29.6 ± 6.4/ 27.6 ± 6.0*

89.2 ± 15.0/78.1 ± 11.5*

NA

NA

4.93 ± 0.68/4.91 ± 0.42

NA

Santana et al. 2004^c [40]

29.18 ± 7.78/–

89.36 ± 15.23/–

NA

TC (mmol/L): 4.71 ± 0.98/–

HDL (mmol/L): 1.01 ± 0.2/–

LDL (mmol/L): 3.10 ± 0.86/–

TGL (mmol/L): 1.26 ± 0.67/–

4.48 ± 0.59/–

NA

Soares et al. 2016 [27]

29.8 ± 6.1/–

95.4 ± 15.8/–

NA

TC (mmol/L): NA

HDL (mmol/L): 1.13 ± 0.35/–

LDL (mmol/L): 2.3(1.81–2.69)/–

TGL (mmol/L): 1.39(0.71–1.85)/–

4.38 ± 0.53/–

1.9(1.3–3.3)/–

Wanderley et al. 2018 [49]

29.9 ± 5.28/–

92.15 ± 10.72/–

SBP: 123.15 ± 18.38/–

DBP: 79.13 ± 11.00/–

TC (mmol/L): 4.73 ± 0.9/–

HDL (mmol/L): 1.28 ± 0.33/–

LDL (mmol/L): 3.03 ± 0.85/–

TGL (mmol/L): 1.25 ± 0.67/–

4.87 ± 0.36/–

NA

Wiltgen et al. 2010^d [43]

31 ± 7.98/ 26.97 ± 3.6*

93.79 ± 18.81/ 79.83 ± 8.37*

SBP: 123.1 ± 16.9/115.2 ± 9.5*

DBP: 78.9 ± 12.3/73.6 ± 8.3

TC (mmol/L): 4.72 ± 1.13/4.27 ± 0.95

HDL (mmol/L): 1.25 ± 0.29/1.42 ± 0.35

LDL (mmol/L): 2.85 ± 0.96/ 2.47 ± 0.81

TGL (mmol/L): 1.12 (0.76–1.6)/ 0.68 (0.47 – 1.05)*

5.02 ± 1.19/ 4.92 ± 0.45

4.53 (2.6–7.7)/ 2.14 (1.4–3.1)*

Xavier et al. 2018 [42]

28.8 ± 8.1/ 22.9 ± 5.9*

97.0(18.0)/ 82.4(20.0)*

NA

TC (mmol/L): 4.92 ± 0.94/ 4.55 ± 0.83*

HDL (mmol/L): 1.19 (0.49) / 1.39 (0.49)*

LDL (mmol/L): 2.97 ± 0.82/2.58 ± 0.72*

TGL (mmol/L): 1.11 (0.97) /0.93 (0.44)*

6.95 ± 11.2/5.78 ± 7.14

2.8 (1.8)/1.59 (1.2)*

BMI-matched studies

Costa et al. 2008 [25]

27.6 ± 5.8/26.7 ± 4.9

87.8 ± 14.3/83.6 ± 10.1

SBP: 118.9 ± 15.2/113.8 ± 10.9

DBP: 79.9 ± 8.9/73.4 ± 10.2*

TC (mmol/L): 4.37 ± 0.62/4.11 ± 0.83

HDL (mmol/L): 1.23 ± 0.34/ 1.54 ± 0.27*

LDL (mmol/L): 2.56 ± 0.65/2.21 ± 0.72*

TGL (mmol/L): 1.16 ± 0.55/1.06 ± 0.68

Lauria et al. 2013 [33]

27.64 ± 5.43/25.99 ± 5.51

91 (83–101)/94 (83–103)

SBP:

120 (110–120)/120 (110–120)

DBP:

80 (70–80)/ 80 (70–80)

TC (mmol/L): 0000000000000004.37 (3.67–4.76)/3.67 (3.21–4.34)*

HDL (mmol/L): 1.11 (0.88–1.29)/1.01 (0.85–1.14)

LDL (mmol/L): 2.77 (2.3–3.26)/2.25 (1.76–2.87)*

TGL (mmol/L): 0.91 (0.73–1.22)/0.8 (0.65–1.06)

Rocha et al. 2011 [39]

29.1 ± 6.17/27.4 ± 6.9

NA

NA

TC (mmol/L): 4.68 ± 0.78/4.28 ± 0.4

HDL (mmol/L): 1.23 ± 0.45/1.51 ± 0.2*

LDL (mmol/L): 2.87 ± 0.65/2.63 ± 0.58

TGL (mmol/L): 1.34 ± 0.74/1.32 ± 0.4

Simões et al. 2017 [41]

28.0 ± 2.4/27.4 ± 2.4

NA

NA

NA

Wiltgen et al. 2009 [47]

29.5 ± 7.5/29.4 ± 5.4

90.6 ± 16.1/ 85.5 ± 11.6*

NA

TC (mmol/L): 4.85 ± 1.11 / 4.2 ± 0.8*

HDL (mmol/L): 1.35 ± 0.27 / 1.32 ± 0.3

LDL (mmol/L) 3.07 ± 0.97/2.46 ± 0.69*

TGL (mmol/L): 1.1 (0.77–1.48)/0.73 (0.54–1.21)*