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Table 1 Clinical characteristics of the study participants

From: Bariatric surgery can acutely modulate ER-stress and inflammation on subcutaneous adipose tissue in non-diabetic patients with obesity

Characteristic

Before surgery

After 3 months

After 6 months

(n = 13)

(n = 13)

(n = 13)

BMI (kg/m2)

42.2 ± 4.2

35.9 ± 4.7*

33.0 ± 2.9###

Body weight (kg)

113.4 ± 14.7

94.2 ± 13.9*

90.1 ± 12.4##

Waist circumference (cm)

123.2 ± 12.0

107.8 ± 7.7

107.2 ± 13.7#

Fat mass (kg)

52.8 ± 9.3

37.8 ± 9.1*

34.4 ± 7.1###

Lean mass (kg)

61.0 ± 5.9

56.4 ± 5.2

55.7 ± 6.1

Fasting glucose (mg/dL)

97.5 ± 25.1

87.0 ± 19.2

82.5 ± 11.6

A1C (%)

5.4 ± 0.7

5.2 ± 0.5

5.1 ± 0.4

Cholesterol (mg/dL)

165 ± 20.5

155.8 ± 27.1

160.9 ± 24.1

HDL cholesterol (mg/dL)

39.0 ± 9.5

39.1 ± 10.6

42.0 ± 10.2

LDL cholesterol (mg/dL)

105.7 ± 20.3

105.3 ± 20.1

100.4 ± 16.5

Triglycerides (mg/dL)

121.5 ± 67.0

86.5 ± 36.2

91.9 ± 40.1

Insulin (mU/L)

17.1 ± 7.7

9.0 ± 5.0

7.5 ± 4.4#

HOMA-IR

2.0 ± 1.0

1.1 ± 0.6*

0.9 ± 0.5#

Systolic BP (mmHg)

136 ± 9.6

113 ± 5.4***

114 ± 7.5###

Diastolic BP (mmHg)

102 ± 6.8

76 ± 5.4***

78.5 ± 6.4###

% of weight loss

NA

− 17%

− 20.50%

% blood glucose reduction

NA

− 12.90%

− 17.50%

% Cholesterol reduction

NA

− 5.50%

− 2.50%

% Triglycerides reduction

NA

− 30.90%

− 26.60%

% LDL reduction

NA

− 0.40%

− 5.00%

% HDL change

NA

− 0.25%

7.40%

  1. Values are given as mean ± SD. One-way ANOVA, post-test Tukey
  2. BMI body mass index, A1C hemoglobin A1C, HDL high-density lipoprotein, LDL low-density lipoprotein, HOMA-IR homeostatic model assessment-insulin resistance; NA not applicable
  3. *,#,$p < 0.05; **,##,$$p < 0.01; ***,###,$$$p < 0.001
  4. * Baseline vs. 3 months
  5. # Baseline vs. 6 months
  6. $ 6 months vs. 3 months